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obophenotype / human-phenotype-ontology

Ontology for the description of human clinical features
http://obophenotype.github.io/human-phenotype-ontology/
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NTR: Renal biopsy: cystine crystals (Lab: pathology: biopsies & morphology) #9133

Closed pnrobinson closed 3 months ago

pnrobinson commented 1 year ago

New term request Renal biopsy: cystine crystals (elthat_100520034404): Kidney

pnrobinson commented 8 months ago

@MickeySegal is that this pathology? https://www.kidney-international.org/article/S0085-2538(15)51432-4/fulltext

@avirosenberg -- could you help define this term? Should we specify which part of the nephron?

MickeySegal commented 8 months ago

https://www.ncbi.nlm.nih.gov/books/NBK1400/ describes "Electron microscopy of the glomeruli reveals fusion of foot processes, thickening of Bowman's membrane, and localization of cystine crystals in interstitial cells". In the article you cite it sounds like the crystals are deposited in many places in the kidney, so the more general term might be best.

pnrobinson commented 3 months ago

@MickeySegal I think this is the most widely used terminology:

Adding new term: