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obophenotype / human-phenotype-ontology

Ontology for the description of human clinical features
http://obophenotype.github.io/human-phenotype-ontology/
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NTR: Liver biopsy: sinusoidal congestion (Lab: pathology: biopsies & morphology) #9157

Closed pnrobinson closed 1 year ago

pnrobinson commented 1 year ago

New term request Liver biopsy: sinusoidal congestion (elthat_100623001137): Hepatic biopsy

pnrobinson commented 1 year ago

Def: Presence of an increased amount of blood in the hepatic capillaries. See Figure in PMID:15270610 Comment: Sinusoidal dilatation and congestion (SDC) in liver biopsy is often the result of venous outflow impairment. This impairment can occur at the level of the small hepatic veins (veno-occlusive disease), large hepatic veins (Budd-Chiari syndrome), or the heart (right-sided heart failure, tricuspid valve disease, constrictive pericarditis). These changes are most pronounced in zone 3 and are often accompanied by hepatocyte atrophy. However, these changes are not specific for venous outflow impairment and can occur in other disorders, such as those associated with sinusoidal infiltration, including sickle cell anemia; hematologic malignancies, malaria, and extramedullary hematopoiesis; and in granulomatous and neoplastic diseases. Dilatation of zone 1 sinusoids has been reported with oral contraceptive use.

Also Hepatic sinusoidal dilatation see https://pubmed.ncbi.nlm.nih.gov/29392360/

pnrobinson commented 1 year ago

@MickeySegal

adding as Hepatic sinusoidal dilatation HP:0035006