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obophenotype / human-phenotype-ontology

Ontology for the description of human clinical features
http://obophenotype.github.io/human-phenotype-ontology/
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NTR: 6-mercaptopurine sensitivity (Triggers or responses: drugs or treatments) #9494

Open pnrobinson opened 1 year ago

pnrobinson commented 1 year ago

New term request 6-mercaptopurine sensitivity (segal_120425154029): 6-MP; 6MP; thiopurines

pnrobinson commented 4 months ago

@MickeySegal Is this referring to https://pubmed.ncbi.nlm.nih.gov/36120820/ ? Please provide more context.

MickeySegal commented 4 months ago

Correct. The drug 6-mercaptopurine, typically given for immune disorders or blood cancers, is not broken down with the normal speed and has toxic effects, typically noticed by effects on blood cells. See also https://omim.org/entry/610460