NTR: Warfarin sensitivity (Triggers or responses: drugs or treatments)

obophenotype / human-phenotype-ontology

Ontology for the description of human clinical features

http://obophenotype.github.io/human-phenotype-ontology/

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NTR: Warfarin sensitivity (Triggers or responses: drugs or treatments) #9501

Open pnrobinson opened 1 year ago

pnrobinson commented 1 year ago

New term request Warfarin sensitivity (elthat_140227172954): Coumarin, coumadin

pnrobinson commented 4 months ago

@MickeySegal please define what you mean. Isn't sensitivity to Warfarin the normal finding?

MickeySegal commented 4 months ago

https://omim.org/entry/301052 "cause severe bleeding during coumarin therapy. Strikingly, the bleeding occurred within the therapeutic ranges of the prothrombin time (PT) and international normalized ratio (INR). In all 3 patients, coumarin therapy caused an unusually selective decrease of factor IX activity to levels below 1 to 3%."

I changed our finding title to "Warfarin sensitivity abnormally high".