mesocardium

[cmungall]

dorsal mesocardium is an only-child

.........po MA:0000072 ! heart ..........po MA:0000098 ! mesocardium *** ...........is_a MA:0000482 ! dorsal mesocardium

are there other types?

Is the meaning of "mesocardium" the same in embryology? If not, is there a synonym that can help distinguish the two?

Original comment by: cmungall

Original Ticket: obo/mouse-anatomy-requests/55

[cmungall]

• assigned_to: nobody --> hayamizu

Original comment by: tfhayamizu

[cmungall]

There appears to be at least two distinct usages for the term "mesocardium." Below is a compilation and attempt at organizing some of the various definitions.

1. The mesentery supporting the embryonic heart. / That part of the embryonic mesentery connecting the heart with the body wall in front and the foregut behind. / Either of the two layers of the embryonic mesentery supporting the embryonic heart in the pericardial cavity. / The double layer of sphlancnic mesoderm supporting the embryonic heart in the pericardial cavity; it disappears before birth. (Note that this may not be true for the mouse.)

1a. Dorsal mesocardium - the part of the mesocardium dorsal to the embryonic heart; it breaks down to form the transverse sinus of the pericardium.

1b. Ventral mesocardium - the part of the mesocardium ventral to the embryonic cardiac tub; transitory in all vertebrates; in higher mammals, it breaks through as soon as its component layers of epicardium make contact with each other.

2. Epicardium covering the blood vessels which enter and leave the heart. / Either of two tubular prolongations of the epicardium that enclose the aorta and pulmonary trunk and the venae cavae and pulmonary veins.

Original comment by: tfhayamizu

[cmungall]

It should be kept in mind that the MA ontology is intended to cover the entire postnatal period for the mouse and, thus, some structures that are considered to be "embryonic" for humans may persist postnally in the mouse. This appears to be true for the "dorsal mesocardium" but not for the "ventral mesocardium".

For clarity, and in accord with the Edinburgh developmental mouse anatomy (EMAPA), MA:0000098 has been renamed "heart mesentery", and the relationship between MA:0000482 "dorsal mesocardium" and "heart mesentery" changed to part_of.

Original comment by: tfhayamizu

[cmungall]

• status: open --> closed-accepted

Original comment by: tfhayamizu