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obophenotype / uberon

An ontology of gross anatomy covering metazoa. Works in concert with https://github.com/obophenotype/cell-ontology
http://obophenotype.github.io/uberon/
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is 'flexor digitorum profundus' definitely a 'forelimb stylopod muscle'? #1479

Open balhoff opened 5 years ago

balhoff commented 5 years ago

I am looking into some conflicts between Uberon and EMAPA. One stems from 'flexor digitorum profundus', which is part of the forearm in EMAPA. The forearm is mapped to UBERON zeugopod. Uberon says this muscle is a 'forelimb stylopod muscle'. I'm no expert but it looks zeugopod-ish in this picture: https://en.wikipedia.org/wiki/Flexor_digitorum_profundus_muscle

Which is right?

tfhayamizu commented 5 years ago

Jim,

I can look into this in a bit more detail, but I believe it depends on how one determines where a muscle is located.

Wikipedia says "The flexor digitorum profundus is a musclehttps://en.wikipedia.org/wiki/Muscle in the forearmhttps://en.wikipedia.org/wiki/Forearm of humanshttps://en.wikipedia.org/wiki/Human that flexes the fingershttps://en.wikipedia.org/wiki/Finger … It is considered an extrinsic hand muscle because it acts on the hand while its muscle belly is located in the forearm."

It appears to originate on the ulna, with attachments to the distal humerus and proximal radius [cid:image001.png@01D4BE3B.5C5D6700], ending in tendons that insert on pharlanges of the digits.

http://knowledge.statpearls.com/chapter/usmle%20step%201/21818/

My opinion is that it should be classified as a forearm (forelimb zeugopod) muscle, since that is where the bulk of the muscle if located. it could be classified as a muscle of both the zeugopod and autopod (if there was such a class), but it appears that mostly only its tendons are located in the hand (autopod).

Does this help?

Terry

From: Jim Balhoff notifications@github.com Reply-To: obophenotype/uberon Subject: [obophenotype/uberon] is 'flexor digitorum profundus' definitely a 'forelimb stylopod muscle'? (#1479)

I am looking into some conflicts between Uberon and EMAPA. One stems from 'flexor digitorum profundus', which is part of the forearm in EMAPA. The forearm is mapped to UBERON zeugopod. Uberon says this muscle is a 'forelimb stylopod muscle'. I'm no export but it looks zeugopod-ish in this picture: https://en.wikipedia.org/wiki/Flexor_digitorum_profundus_muscle

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balhoff commented 5 years ago

Thanks Terry! It doesn't sound like you think that stylopod is right, in any case. Perhaps Uberon should change this to a 'forelimb zeugopod muscle'.

uberon commented 5 years ago

EMAPA I think. But FMA says (or said) upper arm.

In general we have to be wary about giving flexors etc locations using part_of, since the entire muscle often spans segments. But in this case I think forearm is correct.

On Wed, Feb 6, 2019 at 1:19 PM Jim Balhoff notifications@github.com wrote:

I am looking into some conflicts between Uberon and EMAPA. One stems from 'flexor digitorum profundus', which is part of the forearm in EMAPA. The forearm is mapped to UBERON zeugopod. Uberon says this muscle is a 'forelimb stylopod muscle'. I'm no export but it looks zeugopod-ish in this picture: https://en.wikipedia.org/wiki/Flexor_digitorum_profundus_muscle

Which is right?

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