cardiac valve leaflet vs cusp of cardiac valve

[sbello]

Uberon term cardiac valve leaflet (UBERON:0011741) (from EMAPA and MA, no definition) cusp of cardiac valve (UBERON:0006009) (from FMA and NCIT, has definition) plus the child terms of these

Reason for deprecation There is no clear distinction between valve leaflet and cusp in UBERON or in most sources.

Sources using these terms interchangeably

• http://www.vhlab.umn.edu/atlas/anatomy-tutorial/cardiac-valve-nomenclature.shtml
• https://my.clevelandclinic.org/health/body/17067-heart-valves
• https://teachmeanatomy.info/thorax/organs/heart/heart-valves/
• https://www.cardioserv.net/echo-aortic-valve-anatomy/
• https://www.kenhub.com/en/library/anatomy/heart-valves (“While there is a preference for the term leaflet in newer texts, it is often used interchangeably with the term cusp.”)

A few sources make a distinction between cusps and leaflets, with atrioventricular (AV) valves having leaflets and semilunar (SL) valves having cusps

• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209403/
• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232166/ (“The mature valve structures are composed of leaflets (AV) or cusps (semilunar) with supporting structures.”)
• https://www.elsevier.com/resources/anatomy/cardiovascular-system/heart-pericardium/cardiac-valves/21072#article-content (There is a discrepancy in the nomenclature used to describe the components of the valves. The moving portions of the valve are the leaflets. However, for the semilunar valves, they may be referred to as cusps due to their shape)

Currently Uberon has cusp and leaflet terms for:

• aortic valve (SL valve)
• mitral valve (AV valve)
• pulmonary valve (SL valve)
• tricuspid valve (AV valve)

In the case of the tricuspid valve tricuspid valve cusp is a child of tricuspid valve leaflet

Suggested replacement or term to consider My preference is to merge the leaflet and cusp terms into a single term per valve. The merged term would become an exact sibling of the other.

[cmungall]

good analysis, I agree with the course of action

[aleixpuigb]

Thank you for submitting this ticket, I will give a 2 week notice in slack and if nobody is against it, I will proceed to merge leaflet and cusp for each valve. Since tricuspid valves and biscupid valve (atrial valve) receive the name after the number of cusps they contain, I would suggest 'cusp' terms as the winning terms. Do you agree, @sbello?

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