Open ANiknejad opened 10 years ago
this one slipped - let me know if this is a priority or if you want to wait until the linked ticket is resolved
Not a priority, as we already made the integration for the next release of Bgee, without using this stage.
Could that be added please @cmungall ?
I closed this issue, sounds like no more relevant to align HsapDv with HPO, see last comments here
https://github.com/obophenotype/human-phenotype-ontology/issues/5119
This has come up again for us. I think there are two cases that need to be considered (the 3rd is already handled).
@lzehl @UlrikeS91
@tgbugs thanks for bringing this up again on our behalf. We (EBRAINS) have quite a number of researchers from human and rodent studies that would like to register an "adolescent stage" or "young adult stage".
The "prime adult stage" is defined as "A life cycle stage that starts at completion of development and growth of the sexually mature adult animal, and ends before senescence." which leaves at least for some species a life cycle stage within the "post-juvenile adult stage" undefined where sexual maturity is reached before the completion of development. Especially from the neuroscience perspective researchers want/need to point out that they are looking explicitly at subjects in that life cycle stage or not.
For this reason I strongly support @tgbugs suggestion.
id: UBERON:0018241
name: prime adult stage
def: "A life cycle stage that starts at completion of development and growth of the sexually mature adult animal, and ends before senescence." [Bgee:AN, https://github.com/obophenotype/uberon/issues/496]
synonym: "adulthood stage" RELATED []
is_a: UBERON:0000105 ! life cycle stage
relationship: part_of UBERON:0000113 ! post-juvenile adult stage
how should the above be used for eels? The current def doesn't quite apply. What about changing to "starts at the onset of sexual maturity or the cessation of growth, whichever comes last"? cc @ANiknejad
once this is clarified it should be easy to fit in the two new terms
I like that definition, it makes it clear that both sexual maturity and growth must be complete and makes it more temporal so that it is easier to understand for the eel case.
@cmungall I'm not sure if I understand correctly do you just want to redefine "prime adult stage" to include the missing period? That would not solve the problem that some researchers explicitly want to name that short period (sexual mature but not fully developed)
The eel case, if I got this correctly, would be fully developed but not sexually mature? would that not just mean that they are juvenile and then immediately merge into prime adults, because once the hit sexual maturity they are fully developed as well ?
@lzehl prime adult stage already does not contain the missing period, it is just that the current textual definition makes it hard to understand.
@tgbugs yes, it does not contain the missing period. I was just not sure if the plan was to redefine "prime adult" to include the period or if the plan was to define the missing period separately and just refine all definitions. The latter is what we would need within our database. Our current solution is the following: openMINDS_controlledTerms PR 59 I hope this does not collide with the outcome of this issue
Hi Chris,
we would like to propose an 'adolescent stage' with the following draft definition: "A life cycle stage during which the completion of development and growth of the sexually mature organism occurs."
This will match with the design of Uberon (see below) and will precedes UBERON:0018241 ! prime adult stage [def: "A life cycle stage that starts at completion of development and growth of the sexually mature adult animal, and ends before senescence."]
currently in Uberon:
Our suggestion is based on many references, here an example: http://www.ncbi.nlm.nih.gov/pubmed/15251870 "adolescence appears to be a highly conserved developmental stage, its characteristics sculpted to meet common evolutionary pressures that include the avoidance of inbreeding at this time of sexual emergence"
New proposition for Uberon design:
For the usage of 'adolescent' in non-humain animals, please see:
http://www.ncbi.nlm.nih.gov/pubmed/21169902 http://www.ncbi.nlm.nih.gov/pubmed/24102398 http://www.ncbi.nlm.nih.gov/pubmed/15251892 http://www.ncbi.nlm.nih.gov/pubmed/25204637
Open to discussion, best regards,
Anne