integumental exocrine gland

obophenotype / uberon

An ontology of gross anatomy covering metazoa. Works in concert with https://github.com/obophenotype/cell-ontology

http://obophenotype.github.io/uberon/

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integumental exocrine gland #612

Closed dosumis closed 9 years ago

dosumis commented 9 years ago

There are similarities in development and functioning between many exocrine glands of the integument. It would be good to have a gropuing class for these:

integumental exocrine gland EquivalentTo: 'exocrine gland' that 'part of' some 'integumentary system'

cmungall commented 9 years ago

Currently we have 'skin gland' which is both too specific (location*) and too generic (gland type).

We could have a class 'integumental gland' to group these. Should we have 'integument endocrone gland' and ex+end subclasses for skin to balance these? Feels like inflation. How many integument/skin endocrine glands are there? Maybe we can get away with only integumental as a grouping.

skin is often used interchangeably with integument, but in uberon skin=epidermis+dermis, whereas integumental system is more generally applicable

cmungall commented 9 years ago

Actually we already have UBERON:0003297 ! gland of integumental system

So I'll add as a subclass for the exocrine. All of the existing subclasses will reclassify here automatically, with the exception of :

UBERON:0002419 ! skin gland
UBERON:0013230 ! gland of nictitating membrane
UBERON:0013645 ! gular gland
UBERON:0003605 ! eye skin gland
UBERON:0007771 ! epidermis gland
UBERON:0012177 ! skin apocrine gland

Which are grouping classes and are not explicitly asserted to be exocrine (but seems unlikely any are endocrine?)

cmungall commented 9 years ago

This paper argues that the skin is an endocrine gland. http://www.ncbi.nlm.nih.gov/pubmed/16982574

Don't think we'll implement this though...

cmungall commented 9 years ago

Extending query to composite-metazoa. Two more that won't auto-classify under integumental exocrine gland:

FBbt:00000409 ! anterior spiracular gland (Drosophila)
FBbt:00000435 ! posterior spiracular gland (Drosophila)

FBbt is uncommitted w.r.t exocrine vs endocrine. It seems insect spiracular and epitracheal glands are a mix? E.g. http://books.google.com/books?id=lv-QOdPBAYAC&pg=PA256&lpg=PA256&dq=spiracular+glands+drosophila+exocrine&source=bl&ots=pzhQ_U6G_F&sig=sISZ7Aic8am4FsCxIQ_JvcPlyE4&hl=en&sa=X&ei=4mpuVOblMsiyogTt74GoCA&ved=0CB4Q6AEwAA#v=onepage&q=spiracular%20glands%20&f=false