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obophenotype / upheno

The Unified Phenotype Ontology (uPheno) integrates multiple phenotype ontologies into a unified cross-species phenotype ontology.
https://obophenotype.github.io/upheno/
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why did 'abnormal resistance to chemical entity' become 'whole organism'? #741

Closed pfey03 closed 3 years ago

pfey03 commented 3 years ago

I came about this issue https://github.com/obophenotype/upheno/pull/491 Why simple abrnormalResistanceToChemicalEntity were changed to whole organism terms? Is a cell a whole organism and I can use them? it's weird.

Why making this term whole organism when single cells also need to use it?

matentzn commented 3 years ago

They need to be distinguished - if you want to annotate that a part of the organism became abnormally resistant to a chemical (but not necessarily the whole), that needs a different pattern. I think this pattern is important for toxicological and pharmacological concerns - here we really care about how the whole organism behaves when a drug is administered, not just a single cell.

That said - single cell organisms are covered by this pattern!

pfey03 commented 3 years ago

OK thanks Nico!