obophenotype / upheno

The Unified Phenotype Ontology (uPheno) integrates multiple phenotype ontologies into a unified cross-species phenotype ontology.
https://obophenotype.github.io/upheno/
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Coordinate neoplasm logical def across MP and HP #88

Closed obophenotype-user closed 8 years ago

obophenotype-user commented 9 years ago

Originally reported on Google Code with ID 87

Please change the logical definitions to read:
In cases where we are specifying a tissue or organ:

'has part' some
(present
and (('inheres in' some neoplasm) and ('occurs in' some [anatomy]))
and ('has component some abnormal))

For example:
increased liver tumor incidence (MP)
Neoplasm of the liver (HP)

Reported by vasilevs@ohsu.edu on 2015-02-11 22:12:58

obophenotype-user commented 9 years ago
In MP, the increased tumor incidence term are going to be modeled as:

abnormal classified tumor incidence
def: an anomaly in the expected number of tumors with a specific classification type
in a given population in a given time period
To do: change label to include neoplasm
To do: need domain and range constraints

‘has part' some 
(‘susceptible toward’ and (‘inheres in’ some (neoplasm and (‘part of’ some anatomy)))
and ('has qualifier' some abnormal))

---
increased organ/body region tumor incidence
def: greater than the expected number of tumors originating in a specific body region
or organ in a given population in a given time period

'has part' some 
(‘increased susceptibility toward’ and ('inheres in' some (neoplasm and (‘part of’
some anatomy))) and ('has qualifier' some abnormal))
--
increased organ/body region tumor incidence
greater than the expected number of tumors originating in a specific body region or
organ in a given population in a given time period

'has part' some 
(‘decreased susceptibility toward’ and ('inheres in' some (neoplasm and (‘part of’
some anatomy))) and ('has qualifier' some abnormal))

This will not be the same in HP though. Not sure if we want to coordinate these somehow?

Reported by vasilevs@ohsu.edu on 2015-02-12 21:47:54

drseb commented 8 years ago

I think there was a decision when @cindyJax and I met. Closing and making a ticket here: https://github.com/obophenotype/mammalian-phenotype-ontology/issues/2156