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oborel / obo-relations

RO is an ontology of relations for use with biological ontologies
http://oborel.github.io/
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relationship between an intrinsic neuron and its neuropil of innervation #754

Open Clare72 opened 10 months ago

Clare72 commented 10 months ago

Ideally, intrinsic neurons have all of their synapses restricted to a particular region of the CNS. In real life there may be a few stray synapses just outside the region.

Label: 'synapses restricted to region' Exact synonym: 'intrinsic to' Definition: 'A relationship between a neuron and a region, where the neuron has essentially all of its synapses in that region.' Comment: 'Relationship may still be used if a very small number of synapses fall slightly outside the boundaries of the region.' Parent: RO:0013001 ('has synaptic IO in region') Domain: CL:0000540 ('neuron') - will be inherited from 'has synaptic terminal in'

I don't think we want to make this a subproperty of input and output relationships, in case there are neurons that do not have one or the other - some sensory neurons might not have synaptic inputs(?)

related to https://github.com/FlyBase/drosophila-anatomy-developmental-ontology/issues/1626

addiehl commented 9 months ago

Suggested that text definition be based on parent property phrasing (per David OS):

A relationship between a neuron and a region, where all of the functionally relevant input and output synapses are in that region.

Add a comment that any class using this relation should not have another restriction using this relation to a non-overlapping region.