Closed verne91 closed 3 years ago
Hello, I came across the segmentation fault at the very beginning of running Shapeit4.
shapeit4 --input 22.snps..vcf.gz --map chr22.b37.gmap.gz --region 22 --use-PS 0.0001 --thread 4 --log 22.phased.log --output 22.phased.vcf SHAPEIT * Author : Olivier DELANEAU, University of Lausanne * Contact : olivier.delaneau@gmail.com * Version : 4.1.3 * Run date : 15/10/2020 - 10:13:30 Files: * Input VCF : [22.snps.vcf.gz] * Genetic Map : [chr22.b37.gmap.gz] * Output VCF : [22.phased.vcf] * Output LOG : [22.phased.log] Parameters: * Seed : 15052011 * Threads : 4 threads * MCMC : 15 iterations [5b + 1p + 1b + 1p + 1b + 1p + 5m] * PBWT : Depth of PBWT neighbours to condition on: 4 * PBWT : Store indexes at variants [MAC>=2 / MDR<=0.5 / Dist=0.02 cM] * HMM : K is variable / min W is 2.50cM / Ne is 15000 * HMM : Recombination rates given by genetic map * HMM : Inform phasing using VCF/PS field / Error rate of PS field is 0.0001 * HMM : !AVX2 optimization inactive! * IBD2 : length>=3.00cM [N>=150 / MAF>=0.010 / MDR<=0.500] Initialization: * VCF/BCF scanning [N=2 / L=70040 / Reg=22] (0.53s) * VCF/BCF parsing [Hom=31.5% / Het=68.2% / Pha=9.031% / Mis=0.3%] (0.53s) * GMAP parsing [n=45329] (0.06s) * cM interpolation [s=17762 / i=52278] (0.01s) * PBWT indexing [l=2769] (0.00s) * HAP update (0.00s) * H2V transpose (0.00s) * IBD2 constraints [#inds=0 / #pairs=0] (0.01s) * PBWT phase sweep (0.01s) * Build genotype graphs [seg=31841] (0.00s) Burn-in iteration [1/5] * V2H transpose (0.00s) Segmentation fault (core dumped)
I just have two samples here. If I need the reference panel, which one is the best? Could you provide the link to download it?
Thanks!
Hi,
Two samples? Yes you definitely need a reference panel.
If you work with human data:
Otherwise, there are plenty of other population specific panels, but not sure they are easily accessible.
Best,
Hello, I came across the segmentation fault at the very beginning of running Shapeit4.
I just have two samples here. If I need the reference panel, which one is the best? Could you provide the link to download it?
Thanks!