Bio-Formats is a Java library for reading and writing data in life sciences image file formats. It is developed by the Open Microscopy Environment. Bio-Formats is released under the GNU General Public License (GPL); commercial licenses are available from Glencoe Software.
Tischi recently asked about what he considered "missing/loss metadata". After some testing, we found the following:
When reading and then writing with B-F importer/exporter, the original metadata annotation does not get included in the OME-XML of the xy-1.ome.tiff.
cc: @tischi