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open-connectome-classes / StatConn-Spring-2015-Info

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Lecture 2 Question: Neural Plasticity #38

Open ajulian3 opened 9 years ago

ajulian3 commented 9 years ago

Taking into account the growth of a brain along with the ever changing structure during adolescence, how would we create an algorithm to detect neuron frequency taking into account the neural plasticity of the brain?

gkiar commented 9 years ago

How would you do it?

ajulian3 commented 9 years ago

My technique would be to at first run a standardization model of neuron's locations and then through using KNN-algorithm to determine where the neural activity is centralized during the neural plasticity period and then eventually compare with other subjects to calculate statistical accuracy and significance.

gkiar commented 9 years ago

Interesting. What do you define as the "neural plasticity period"? Would you expect other subjects to have the same regions exhibiting the same behavior on a neuronal level, or would you use some parcellation scheme to make the data more coarse?