open2c / pairtools

Extract 3D contacts (.pairs) from sequencing alignments
MIT License
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type of UU (unique-unique) is close to each other #104

Open wbszhu opened 3 years ago

wbszhu commented 3 years ago

Hi @Anton, I am using pairtools to parse the hichip data, choosing to keep only the type UU. But I find that it contains a certain number of pairs that are very close (<100bp). I wanna know whether this part should be marked as self-ligate.

UU pairs

A00545: 76:HW7 7KDSXY:1 :2345:17689:17065 chr1 2607 chr1 2616 A00543:178 : HVFNHDSXY:1 :1637 : 31684: 34100 chr1 4421 chr1 4476 A00543 :178 :HVFNHDSXY :1: 1649: 20039: 30843 chr1 28651 chr1 28718 A00543: 178 :HVF NHDSXY :1 : 1365: 30942:33692 chr1 30812 chr1 30820 A00545: 76:HW7 7KDSXY:1 :1673: 9001: 29794 chr1 40995 chr1 41030 A00543 :178 : HVFNHDSXY :1:1408:5647 :21574 chr1 41637 chr1 41645

luzhang.