New trials at ClinicalTrials.gov via RSS feed

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I suggest, that if our current submission asks for revisions, that we query the editors if they agree that the ClinicalTrials.gov data below should be added. Note that the Cochrane review did not include

In response to last week's article in the NEJM about the proposed FDAAA for proposed federal requirements of submission of trial results to ClinicalTrials.gov, below is a search of https://clinicaltrials.gov/ct2/search/advanced with:

Search terms: hypertonic random* Conditions: bronchiolitis Study Type: Interventions Study Results: Studies with results

Yielded 5 entries:

1. NCT01238848 by Espelt and last updated July, 2012.
   • No evidence of publishing (neither lists RCTs nor matches any existing data we have)
   • Addendum 2/22/2014: no evidence of publication to date
   • Has usable length of stay data.
2. NCT01276821 by Khanal and last updated April, 2013.
   • No evidence of publishing (neither lists RCTs nor matches any existing data we have)
   • Addendum 2/22/2014: no evidence of publication to date
   • Has usable symptoms data.
3. NCT01488448 by Silver and last updated Sept, 2014..
   • No evidence of publishing (neither lists RCTs nor matches any existing data we have)
   • Addendum 2/22/2014: no evidence of publication to date
   • Has unusable length of stay data. Reports medians and IQRs.
   • Addendum 2/22/2014: this data can be used by conversion described at http://handbook.cochrane.org/chapter_7/7_7_3_5_mediansand_interquartile_ranges.htm (if we think the data is not skewed)
4. NCT01247064 by Florin.
   • We have this
5. NCT00619918 by Wu.
   • We have this

Potential revised forest plots attached:

• LOS data weaker, but positive
• Symptoms data now negative

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For @openMetaAnalysis/hypertonic-saline

1/13/2015: RSS feed alerted by new trial results from https://clinicaltrials.gov/ct2/show/NCT02045238

Addendum 2/22/2015: High rate of drop out in the normal saline group; however, meets criteria for inclusion.