openbiox / UCSCXenaShiny

📊 An R package for interactively exploring UCSC Xena https://xenabrowser.net/datapages/; Book: https://lishensuo.github.io/UCSCXenaShiny_Book; App online: https://shiny.hiplot.cn/ucsc-xena-shiny/, https://shiny.zhoulab.ac.cn/UCSCXenaShiny
https://openbiox.github.io/UCSCXenaShiny/
GNU General Public License v3.0
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Why is the “mutation” genomic profile missing from the "Molecular Profile HR Cox analysis" module? #352

Closed quiquemedina closed 1 month ago

quiquemedina commented 1 month ago

Dear XenaShiny developers,

I noticed that the “mutation” genomic profile is missing from the "Molecular Profile HR Cox analysis" module.

Since the mutation profile is available in the log_rank survival analysis, I am unsure why the profile is missing from the selection options in the HR Cox analysis. • HR Cox analysis: The "mutation" profile option is absent. • log_rank survival analysis: The "mutation" profile option is present.

Specificaly: UCSCXenaShiny v1.1.8 based on UCSCXenaTools v1.4.8

In R manual,that data type also missing: data_type: choose gene profile type, including "mRNA","transcript","methylation","miRNA","protein","cnv"

R Cox analysis: mutation ´profile option is absent image

Log rank analysis: mutation ´profile option is present image

lishensuo commented 1 month ago

Thanks for the suggestion. We have added the 'mutation' profile for the Cox analysis of TCGA module in the latest update.

quiquemedina commented 1 month ago

Great! I checked it, and it's working fine. Please keep in mind to update the info in the "help" (R studio), so the clients can call it.

data_type | choose gene profile type, including "mRNA","transcript","methylation","miRNA","protein","cnv" to include "mutation"

vis_unicox_tree( Gene = "TP53", measure = "OS", data_type = "mutation", use_optimal_cutoff = FALSE, values = c("grey", "#E31A1C", "#377DB8"), opt_pancan = .opt_pancan )

Regards, Enrique

lishensuo commented 1 month ago

Thanks for your reminder. We will optimize it in the next commit.