Flux-Samplig: Cannot escape sampling region, model seems to be numerically unstable. Reporting the model

[brunorbqi]

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Question

I gave tried to make a flux samplig for my model as following: mfg_bruc = cobra.io.read_sbml_model("iRAW-iBP.xml")

pfba_solution = cobra.flux_analysis.pfba(mfg_bruc) opt_value = pfba_solution["biomass_BA"]

with mfg_bruc:

mfg_bruc.reactions.get_by_id("biomass_BA").lower_bound = opt_value*.95

%time mfg_bruc_samples = sample(mfg_bruc, 10000, processes=4)

At the end, I got the following error : RuntimeError: Cannot escape sampling region, model seems to be numerically unstable. Reporting the model.

How can I fix this error ?! Best regards

[cdiener]

Hi thanks for the report. Can you share your model, so we can take a look what is going on?

[cdiener]

Closing because no response received.