When hydrogens have map indices, Chem.FindMolChiralCenters(molecule, includeUnassigned=True) will flag non chiral carbons as potential chiral centers. This seems to happen because rdkit considers symmetric atoms with map indices nonequivalent.
See this comment for more details:
https://github.com/openforcefield/openforcefield/issues/146#issuecomment-489239497
ChayaSt
commented
5 years ago
When hydrogens have map indices,
Chem.FindMolChiralCenters(molecule, includeUnassigned=True)will flag non chiral carbons as potential chiral centers. This seems to happen because rdkit considers symmetric atoms with map indices nonequivalent. See this comment for more details: https://github.com/openforcefield/openforcefield/issues/146#issuecomment-489239497