openjournals / brief-ideas

The Journal of Brief Ideas
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Hello #170

Closed vnorris closed 5 years ago

vnorris commented 5 years ago

In a recent submission pending acceptance, I made a stupid error and wrote 'opposed by counterflows' when I should have written 'accompanied by flows'. Would you mind correcting it? The Abstract should read:

"Transcription causes a displacement of the transcribed DNA relative to the transcribing RNA polymerases whilst translation causes a displacement of the translated mRNA relative to the translating ribosomes. In the crowded cytoplasm, reptation plays a role in coordinating these displacements; as a result, there are intracellular streams or flows. In bacteria, the coupling of the transcription and translation of highly expressed genes gives rise to flows of nascent mRNA and nascent proteins that are accompanied by flows of transcribed DNA; the RNA polymerases and ribosomes implicated in these processes remain relatively static. This streaming creates a multitude of vortices in the cytoplasm as well as in the membrane (in the case of nascent membrane proteins). This streaming may also cause parts of the chromosome to gyrate and even the whole chromosome to pirouette. These intracellular movements, which are fundamental to the structuring of the cell, may be orchestrated by the replication of DNA (in which both the DNA and the replication factories themselves are believed to move). Such structuring of the cell by DNA replication constitutes an important mechanism whereby the nature of the execution of the cell cycle affects the phenotype."

Sorry about this. Vic

physicsdavid commented 5 years ago

Hi Vic,

This paper was already approved and published. Perhaps you could add a note in the comments below the paper highlighting the correction.

Best wishes, David

vnorris commented 5 years ago

Dear David,

Thanks. I have tried to add this as a comment:

"In the above, 'opposed by counter-flows' should be replaced by 'accompanied by' to give: In bacteria, the coupling of the transcription and translation of highly expressed genes gives rise to flows of nascent mRNA and nascent proteins that are accompanied by flows of transcribed DNA; the RNA polymerases and ribosomes implicated in these processes remain relatively static."

Unfortunately, I don't seem to have succeeded. Maybe there is a lag between my writing the comment and your system inserting it?

Best wishes,

Vic

On Friday, January 25, 2019 01:29 AM CAT, David Harris notifications@github.com wrote:

Hi Vic,

This paper was already approved and published. Perhaps you could add a note in the comments below the paper highlighting the correction.

Best wishes, David

-- You are receiving this because you authored the thread. Reply to this email directly or view it on GitHub: https://github.com/openjournals/brief-ideas/issues/170#issuecomment-457397867 -- Vic Norris Emeritus Professor of Biology Laboratory of Microbiology Signals and Microenvironment University of Rouen 76821 Mont Saint Aignan France

Tel 02 35 71 07 91 email victor.norris@univ-rouen.fr

physicsdavid commented 5 years ago

I don’t see it there either. Strange! We’ll look into it /cc @arfon

vnorris commented 5 years ago

Thanks, David. Actually, I tried to correct the stupid error almost immediately after submission but the system seems to have trundled on regardless. Maybe the original could be deleted and the corrected version published as a new entry

On Friday, January 25, 2019 12:31 PM CAT, David Harris notifications@github.com wrote:

I don’t see it there either. Strange! We’ll look into it /cc @arfon

-- You are receiving this because you authored the thread. Reply to this email directly or view it on GitHub: https://github.com/openjournals/brief-ideas/issues/170#issuecomment-457528765 -- Vic Norris Emeritus Professor of Biology Laboratory of Microbiology Signals and Microenvironment University of Rouen 76821 Mont Saint Aignan France

Tel 02 35 71 07 91 email victor.norris@univ-rouen.fr

arfon commented 5 years ago

Could you please try adding the comment again @vnorris?

vnorris commented 5 years ago

The abstract contains an error and 'opposed by counterflows' should be replaced by 'accompanied by flows'. The sentence should read:

"In bacteria, the coupling of the transcription and translation of highly expressed genes gives rise to flows of nascent mRNA and nascent proteins that are accompanied by flows of transcribed DNA; the RNA polymerases and ribosomes implicated in these processes remain relatively static. "

vnorris commented 5 years ago

Dear Arfon, OK, I have done it - has it worked? All the best, Vic

On Friday, January 25, 2019 04:58 PM CAT, Arfon Smith notifications@github.com wrote:

Could you please try adding the comment again @vnorris?

-- You are receiving this because you were mentioned. Reply to this email directly or view it on GitHub: https://github.com/openjournals/brief-ideas/issues/170#issuecomment-457599114 -- Vic Norris Emeritus Professor of Biology Laboratory of Microbiology Signals and Microenvironment University of Rouen 76821 Mont Saint Aignan France

Tel 02 35 71 07 91 email victor.norris@univ-rouen.fr

arfon commented 5 years ago

Actually, it looks like the easiest thing to do here it to create an entirely new idea. Please resubmit.

vnorris commented 5 years ago

Dear Arfon,

Can you delete the old one first to avoid confusion? Sorry about my original stupidity ...

All the best,

Vic

On Saturday, January 26, 2019 02:21 PM CAT, Arfon Smith notifications@github.com wrote:

Actually, it looks like the easiest thing to do here it to create an entirely new idea. Please resubmit.

-- You are receiving this because you were mentioned. Reply to this email directly or view it on GitHub: https://github.com/openjournals/brief-ideas/issues/170#issuecomment-457826955 -- Vic Norris Emeritus Professor of Biology Laboratory of Microbiology Signals and Microenvironment University of Rouen 76821 Mont Saint Aignan France

Tel 02 35 71 07 91 email victor.norris@univ-rouen.fr

arfon commented 5 years ago

OK, it should be deleted.

On Sat, Jan 26, 2019 at 8:39 AM vnorris notifications@github.com wrote:

Dear Arfon,

Can you delete the old one first to avoid confusion? Sorry about my original stupidity ...

All the best,

Vic

On Saturday, January 26, 2019 02:21 PM CAT, Arfon Smith < notifications@github.com> wrote:

Actually, it looks like the easiest thing to do here it to create an entirely new idea. Please resubmit.

-- You are receiving this because you were mentioned. Reply to this email directly or view it on GitHub:

https://github.com/openjournals/brief-ideas/issues/170#issuecomment-457826955

Vic Norris Emeritus Professor of Biology Laboratory of Microbiology Signals and Microenvironment University of Rouen 76821 Mont Saint Aignan France

Tel 02 35 71 07 91 email victor.norris@univ-rouen.fr

— You are receiving this because you were mentioned. Reply to this email directly, view it on GitHub https://github.com/openjournals/brief-ideas/issues/170#issuecomment-457831937, or mute the thread https://github.com/notifications/unsubscribe-auth/AAARg-YaFZWfUn-yDm2ERcylVeZQcKGjks5vHFqrgaJpZM4Z3RXx .

vnorris commented 5 years ago

Dear David and Arfon,

When I search for "Norris" on your journal's site, I still find the original submission along with "This idea was not accepted into the Journal of Brief Ideas." Would you please delete it and replace it with the corrected version? Of course, the problem originated with my own error. Sorry to bother you with this.

Best wishes,

Vic

On Saturday, January 26, 2019 04:02 PM CAT, Arfon Smith notifications@github.com wrote:

OK, it should be deleted.

On Sat, Jan 26, 2019 at 8:39 AM vnorris notifications@github.com wrote:

Dear Arfon,

Can you delete the old one first to avoid confusion? Sorry about my original stupidity ...

All the best,

Vic

On Saturday, January 26, 2019 02:21 PM CAT, Arfon Smith < notifications@github.com> wrote:

Actually, it looks like the easiest thing to do here it to create an entirely new idea. Please resubmit.

On Friday, January 25, 2019 12:31 PM CAT, David Harris notifications@github.com wrote:

I don’t see it there either. Strange! We’ll look into it /cc @arfon

-- You are receiving this because you were mentioned. Reply to this email directly or view it on GitHub:

https://github.com/openjournals/brief-ideas/issues/170#issuecomment-457826955

Vic Norris Emeritus Professor of Biology Laboratory of Microbiology Signals and Microenvironment University of Rouen 76821 Mont Saint Aignan France

Tel 02 35 71 07 91 email victor.norris@univ-rouen.fr

— You are receiving this because you were mentioned. Reply to this email directly, view it on GitHub https://github.com/openjournals/brief-ideas/issues/170#issuecomment-457831937, or mute the thread https://github.com/notifications/unsubscribe-auth/AAARg-YaFZWfUn-yDm2ERcylVeZQcKGjks5vHFqrgaJpZM4Z3RXx .

-- You are receiving this because you were mentioned. Reply to this email directly or view it on GitHub: https://github.com/openjournals/brief-ideas/issues/170#issuecomment-457833657 -- Vic Norris Emeritus Professor of Biology Laboratory of Microbiology Signals and Microenvironment University of Rouen 76821 Mont Saint Aignan France

Tel 02 35 71 07 91 email victor.norris@univ-rouen.fr

vnorris commented 5 years ago

Dear Arfon and David,

Your robot just sent me this: "Hi, Vic Norris. I'm sorry to say that your idea Transcription, translation and DNA replication cause intracellular streaming and chromosome pirouetting has not been accepted by the Journal of Brief Ideas. If you'd like to read more about our publication standards please visit http://beta.briefideas.org/about#standards Yours, the Journal of Brief Ideas robot."

Unfortunately, the incorrect version of my idea is still on your site along with the information that it has been rejected. This is the worst of all worlds. Please either replace it with the correct version or delete it totally.

Best wishes,

Vic

On Saturday, January 26, 2019 04:02 PM CAT, Arfon Smith notifications@github.com wrote:

OK, it should be deleted.

On Sat, Jan 26, 2019 at 8:39 AM vnorris notifications@github.com wrote:

Dear Arfon,

Can you delete the old one first to avoid confusion? Sorry about my original stupidity ...

All the best,

Vic

On Saturday, January 26, 2019 02:21 PM CAT, Arfon Smith < notifications@github.com> wrote:

Actually, it looks like the easiest thing to do here it to create an entirely new idea. Please resubmit.

-- You are receiving this because you were mentioned. Reply to this email directly or view it on GitHub:

https://github.com/openjournals/brief-ideas/issues/170#issuecomment-457826955

Vic Norris Emeritus Professor of Biology Laboratory of Microbiology Signals and Microenvironment University of Rouen 76821 Mont Saint Aignan France

Tel 02 35 71 07 91 email victor.norris@univ-rouen.fr

— You are receiving this because you were mentioned. Reply to this email directly, view it on GitHub https://github.com/openjournals/brief-ideas/issues/170#issuecomment-457831937, or mute the thread https://github.com/notifications/unsubscribe-auth/AAARg-YaFZWfUn-yDm2ERcylVeZQcKGjks5vHFqrgaJpZM4Z3RXx .

-- You are receiving this because you were mentioned. Reply to this email directly or view it on GitHub: https://github.com/openjournals/brief-ideas/issues/170#issuecomment-457833657 -- Vic Norris Emeritus Professor of Biology Laboratory of Microbiology Signals and Microenvironment University of Rouen 76821 Mont Saint Aignan France

Tel 02 35 71 07 91 email victor.norris@univ-rouen.fr