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openpharma / brms.mmrm

R package to run Bayesian MMRMs using {brms}
https://openpharma.github.io/brms.mmrm/
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cLDA for informative prior archetypes? #125

Closed wlandau closed 3 months ago

wlandau commented 3 months ago

c.f. https://github.com/openpharma/brms.mmrm/discussions/112, https://stackoverflow.com/questions/78799680/clda-constraint-for-discrete-time-models-in-r-formulas.

wlandau commented 3 months ago

I tried a bunch of attempts, and I think this needs to be coded for each archetype individually.

wlandau commented 3 months ago

Also, we can't support cLDA for brm_archetype_average_cells() or brm_archetype_average_effects() because then we can no longer guarantee that certain effects are averages of the others.

wlandau commented 3 months ago

Fixed in #126