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Repository for discussion of OpenSAFELY codelists
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*MEDICINE* Long-acting insulin #270

Closed a-d-brown closed 10 months ago

a-d-brown commented 10 months ago

User Requirements Identify patients who are taking a long-acting insulin. This will be used alongside a GLP-1 codelist to identify a specific cohort of patients and assess the impact of the impact of GLP-1s being prescribed for weight loss.

Search Terms

Inclusion Criteria for Codes

Exclusion Criteria for Codes

Borderline Cases to Highlight

Codelist https://www.opencodelists.org/codelist/user/Andrew/insulin-long-acting-basal/646512fd/

chrisjwood16 commented 10 months ago

BNF defines long-acting insulins - https://bnf.nice.org.uk/treatment-summaries/insulin/ Their definition includes Protamine zinc insulin (0601012U0), Insulin zinc suspension (0601012G0)/Insulin zinc suspension (Crystalline) (0601012N0) so could include those for completeness. But also note seem to be discontinued in UK and no prescriptions since 2019 so could equally exclude on that basis.

For long-acting insulin in combo with GLP-1 - will this be a separate codelist (or included in GLP-1 codelist)?

a-d-brown commented 10 months ago

Thanks Chris, yeah I spent a while sifting through all the zinc cases (sorry perhaps should have mentioned in notes). As far as I could tell all the relevant cases had been discontinued.

Yes, a separate codelist is being developed specifically to identify the products which are a combination of long-acting insulin with a GLP-1.

chrisjwood16 commented 10 months ago

Great. Please just add "insulin products discontinued in the UK (protamine zinc insulin, insulin zinc suspension)" to the exclusions above and I'm happy to approve.

a-d-brown commented 10 months ago

Added, thanks. Here is the dm+d version for completeness: https://www.opencodelists.org/codelist/user/Andrew/insulin-long-acting-basal-dmd/02da061f/#full-list