*MEDICATION*: Pharmacy First - Acute Otitis Media treatment

[chrisjwood16]

User requirements

This codelist is used to identify supply of any medication included in the Pharmacy First Patient Group Directions for treatment of acute otitis media.

Sensitivity versus specificity

Specific to only the strength/formulations included in the PGDs for acute otitis media (including both brands and generics).

Relevant definitions or links to important reference sources

PGDs: https://www.england.nhs.uk/wp-content/uploads/2023/11/PRN01010-7a.-Acute-otitis-media-phenazone-lidocaine-ear-drops-patient-group-direction-Pharmacy-First.pdf https://www.england.nhs.uk/wp-content/uploads/2023/11/PRN01010-7b.-Acute-otitis-media-amoxicillin-patient-group-direction-Pharmacy-First.pdf https://www.england.nhs.uk/wp-content/uploads/2023/11/PRN01010-7c.-Acute-otitis-media-clarithromycin-patient-group-direction-Pharmacy-First.pdf https://www.england.nhs.uk/wp-content/uploads/2023/11/PRN01010-7d.-Acute-otitis-media-erythromycin-patient-group-direction-Pharmacy-First.pdf

Coding system

dm+d

Existing relevant codelists

N/A

Search terms / synonyms / search strategy

• Otigo
• Phenazone
• Amoxicillin
• Clarithromycin
• Erythromycin

Inclusion criteria for codes

• Otigo®(phenazone 40mg/lidocaine hydrochloride 10mg/g) ear drops, solution
• Amoxicillin 250mg capsules
• Amoxicillin 500mg capsules
• Amoxicillin 125mg/5mL oral suspension (or oral solution)
• Amoxicillin 125mg/5mL sugar free oral suspension (or oral solution)
• Amoxicillin 250mg/5mL oral suspension (or oral solution)
• Amoxicillin 250mg/5mL sugar free oral suspension (or oral solution)
• Amoxicillin 500mg/5mL sugar free oral suspension (or oral solution)
• Clarithromycin 250mg tablets
• Clarithromycin 500mg tablets
• Clarithromycin 125mg/5mL oral suspension (or oral solution)
• Clarithromycin 250mg/5mL oral suspension (or oral solution)
• Erythromycin 250mg tablets
• Erythromycin 250mg gastro-resistant tablets
• Erythromycin 500mg tablets
• Erythromycin 125mg/5mL oral suspension (or oral solution)
• Erythromycin 125mg/5mL sugar free oral suspension (or oral solution)
• Erythromycin 250mg/5mL oral suspension (or oral solution)
• Erythromycin 250mg/5mL sugar free oral suspension (or oral solution)
• Erythromycin 500mg/5mL oral suspension (or oral solution)
• Erythromycin 500mg/5mL sugar free oral suspension (or oral solution)

Exclusion criteria for codes

Strengths/formulations not listed above.

Borderline cases

Clarithromycin granules for oral solution, erythromycin capsules - excluded as form not included in PGD.

Final codelist

Published: BNF code format: https://www.opencodelists.org/codelist/opensafely/pharmacy-first-acute-otitis-media-treatment/25601363/

dm+d format: https://www.opencodelists.org/codelist/opensafely/pharmacy-first-acute-otitis-media-treatment-dmd/4122468e/

[a-d-brown]

Consider adding:

• Amix 250 oral suspension (0501013B0BFAIAT)

Otherwise, all looks good. @chrisjwood16

Note, I debated whether amoxicillin syrups were technically distinct here, but it doesn't seem that dm+d has any distinct category for syrups. My understanding is that a syrup is just a sub-classification of an oral solution / suspension. So, I think fine to keep in the codelist.

[chrisjwood16]

Looks like I missed Amix 250. Added here now: https://www.opencodelists.org/codelist/user/chriswood/pharmacy-first-acute-otitis-media-treatment/25601363/

Will keep syrups as I think basically the same. And the rest of the analysis code will ensure we identify the correct things.

[a-d-brown]

Checked - all correct.

[chrisjwood16]

Published: BNF code format: https://www.opencodelists.org/codelist/opensafely/pharmacy-first-acute-otitis-media-treatment/25601363/

dm+d format: https://www.opencodelists.org/codelist/opensafely/pharmacy-first-acute-otitis-media-treatment-dmd/4122468e/