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openvax / mhcflurry

Peptide-MHC I binding affinity prediction
http://openvax.github.io/mhcflurry/
Apache License 2.0
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Regarding output #157

Closed komalhpatil closed 4 years ago

komalhpatil commented 4 years ago

Hello sir, I have tried predicting MHC binding affinity using NetMHCPAn 4.0 server and MHCFlurry both, but I'm not getting consistent results. May I please know the reason behind this issue?

timodonnell commented 4 years ago

NetMHCpan and MHCflurry are different predictive methods, so results will definitely be different between the two. However, if you are seeing large / consistent discrepancies in some cases we'd be interested to know about that, if you can share the peptides and alleles you're looking at. Thanks.

komalhpatil commented 4 years ago

Sure, thanks. Following are a few peptides from our study, GLLLVRPPR GWVIAASFPR GQLSCFLSPR YAETFSSYTDLDK STKIDWFDDTVSSK