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openvax / mhcflurry

Peptide-MHC I binding affinity prediction
http://openvax.github.io/mhcflurry/
Apache License 2.0
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Selenocysteine #184

Closed p-priestley closed 3 years ago

p-priestley commented 3 years ago

Hello,

Thanks for the great tool.

Could you please advise whether you have any support for peptides with the Selenocysteine amino acid (normally represented as 'U') and if so how to specify this in the mhcflurry-predict command?

Peter

timodonnell commented 3 years ago

We do not, unfortunately.

I'd be interested to add this but we don't have much data for U-containing peptides to train on (IEDB seems to have just 3 seleno-peptides for class I). If you're aware of any data sources on MHC/seleno-peptide binding I'd be interested to know.

p-priestley commented 3 years ago

Sorry. I am not aware of any validation data. Thanks for the quick reply.