Difference between "affinity_percentile" and "presentation_percentile"

openvax / mhcflurry

Peptide-MHC I binding affinity prediction

http://openvax.github.io/mhcflurry/

Apache License 2.0

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Difference between "affinity_percentile" and "presentation_percentile" #193

Closed ShanWeera closed 3 years ago

ShanWeera commented 3 years ago

What is the difference between affinity_percentile and presentation_percentile?

timodonnell commented 3 years ago

presentation_percentile is the percentile rank of the presentation score (which combines MHC binding affinity and processing score). affinity_percentile is the percentile rank of the MHC binding affinity alone. Presentation score is experimental. If you are just looking for MHC binding predictions you should use affinity_percentile.