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openvax / neoantigen-vaccine-pipeline

Bioinformatics pipeline for selecting patient-specific cancer neoantigen vaccines
Apache License 2.0
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Identify driver variants #103

Closed iskandr closed 6 years ago

iskandr commented 6 years ago

Match all mutations against known specific variants in CIViC

Also match non-synonymous coding variants against whitelist of known oncogenes (e.g. TP53, MYC, KRAS, NRAS, &c).

Plan: use Tier 1 oncogene list from COSMIC: https://cancer.sanger.ac.uk/cosmic/census?tier=1

julia326 commented 6 years ago

This is being done in Vaxrank now