openvax / neoantigen-vaccine-pipeline

Bioinformatics pipeline for selecting patient-specific cancer neoantigen vaccines
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Long-running steps #125

Open iskandr opened 5 years ago

iskandr commented 5 years ago

Here are steps from a recent run whose benchmarks showed they took more than 1000 seconds:

==> dna_indel_realigner_10.txt <==
2232.3606       0:37:12 7345.22 25516.19        7317.20 7320.92 24.18   2038.69 0.00
==> dna_indel_realigner_11.txt <==
6291.8371       1:44:51 7311.09 25513.62        7281.90 7285.59 793.64  3602.06 0.00
==> dna_indel_realigner_12.txt <==
4230.6952       1:10:30 5818.19 25513.62        5787.84 5791.54 24.73   2894.29 0.00
==> dna_indel_realigner_13.txt <==
1468.8043       0:24:28 7221.28 25513.62        7191.81 7195.53 0.00    1069.15 0.00
==> dna_indel_realigner_14.txt <==
3579.2174       0:59:39 6232.40 25513.62        6201.90 6205.65 4.43    2015.45 0.00
==> dna_indel_realigner_15.txt <==
2926.9650       0:48:46 7081.42 25513.62        7052.04 7055.79 0.00    1964.56 0.00
==> dna_indel_realigner_16.txt <==
3972.0825       1:06:12 7202.23 25513.62        7172.73 7176.40 313.71  2434.78 0.00
==> dna_indel_realigner_17.txt <==
4168.9924       1:09:28 7156.39 25513.62        7127.02 7130.69 0.00    2946.00 0.00
==> dna_indel_realigner_19.txt <==
5485.6922       1:31:25 5961.20 25515.46        5930.61 5934.34 233.41  3154.30 0.00
==> dna_indel_realigner_1.txt <==
6361.7157       1:46:01 7317.08 25513.62        7288.31 7292.02 1305.05 7902.32 0.00
==> dna_indel_realigner_20.txt <==
2541.8745       0:42:21 5274.98 25513.62        5245.59 5249.32 0.08    2276.02 0.00
==> dna_indel_realigner_21.txt <==
==> dna_indel_realigner_22.txt <==
1661.3689       0:27:41 5509.75 25515.47        5481.68 5485.37 0.02    1120.68 0.00
==> dna_indel_realigner_2.txt <==
5512.6300       1:31:52 6227.10 25513.62        6199.05 6202.76 110.49  4104.15 0.00
==> dna_indel_realigner_3.txt <==
3747.2937       1:02:27 7312.88 25513.74        7283.37 7287.06 588.59  4374.61 0.00
==> dna_indel_realigner_4.txt <==
3302.1961       0:55:02 6254.44 25513.62        6226.50 6230.90 0.00    2266.16 0.00
==> dna_indel_realigner_5.txt <==
3000.0765       0:50:00 6466.55 25513.62        6436.05 6439.74 0.00    2389.16 0.00
==> dna_indel_realigner_6.txt <==
3980.8258       1:06:20 5680.93 25513.68        5650.43 5654.19 253.09  2785.27 0.00
==> dna_indel_realigner_7.txt <==
4667.4566       1:17:47 6016.04 25513.62        5986.89 5990.59 0.00    3018.75 0.00
==> dna_indel_realigner_8.txt <==
3179.9276       0:52:59 6304.45 25513.62        6275.17 6278.84 177.08  2060.52 0.00
==> dna_indel_realigner_9.txt <==
2470.5035       0:41:10 7317.67 25513.62        7288.70 7292.44 0.01    2001.30 0.00
==> mutect_10.txt <==
4747.0189       1:19:07 1505.48 4580.24 1482.28 1483.99 3050.38 244.46  0.00
==> mutect_11.txt <==
7434.6895       2:03:54 1752.22 4580.24 1727.98 1730.40 5022.91 265.66  0.00
==> mutect_12.txt <==
5590.2279       1:33:10 1583.18 4580.24 1560.18 1563.48 5369.45 244.69  0.00
==> mutect_13.txt <==
2798.7419       0:46:38 1343.87 4580.24 1318.77 1321.61 1616.30 168.26  0.00
==> mutect_14.txt <==
3846.6900       1:04:06 1417.46 4580.24 1393.11 1397.59 3858.72 171.23  0.00
==> mutect_15.txt <==
3695.7094       1:01:35 1443.46 4580.24 1420.16 1426.62 3539.88 160.98  0.00
==> mutect_16.txt <==
4601.7273       1:16:41 1567.40 4580.24 1543.46 1545.04 2173.40 171.55  0.00
==> mutect_17.txt <==
5116.0675       1:25:16 1538.50 4580.24 1515.50 1518.83 4814.71 164.08  0.00
==> mutect_18.txt <==
2185.7486       0:36:25 1269.51 4580.24 1245.20 1249.70 1631.26 131.03  0.00
==> mutect_19.txt <==
5452.0785       1:30:52 1525.74 4580.24 1501.88 1503.75 1802.42 134.32  0.00
==> mutect_1.txt <==
9886.8023       2:44:46 1996.97 4580.24 1972.92 1976.19 9535.76 425.77  0.00
==> mutect_20.txt <==
3147.6437       0:52:27 1391.55 4580.24 1367.55 1369.04 868.11  126.37  0.00
==> mutect2_10.txt <==
99847.8984      1 day, 3:44:07  1525.08 5387.58 1493.20 1495.17 3506.81 64.66   0.00
==> mutect2_11.txt <==
184300.3277     2 days, 3:11:40 1555.01 5404.02 1523.30 1525.29 6177.75 115.43  0.00
==> mutect2_12.txt <==
154445.7718     1 day, 18:54:05 1501.15 5382.78 1469.77 1471.87 5458.34 97.23   0.00
==> mutect2_13.txt <==
57713.5828      16:01:53        1281.04 5383.56 1249.61 1250.71 1710.05 39.32   0.00
==> mutect2_14.txt <==
109842.1128     1 day, 6:30:42  1460.52 5406.49 1429.01 1430.46 2961.88 69.78   0.00
==> mutect2_15.txt <==
103270.8924     1 day, 4:41:10  1432.85 5401.40 1401.12 1402.50 2156.99 65.73   0.00
==> mutect2_16.txt <==
126177.3335     1 day, 11:02:57 1509.33 5401.82 1477.66 1479.35 3975.56 79.19   0.00
==> mutect2_17.txt <==
160714.2310     1 day, 20:38:34 1508.52 5406.33 1480.32 1482.18 4687.88 100.00  0.00
==> mutect2_18.txt <==
46132.8540      12:48:52        1258.10 5380.63 1227.00 1228.04 423.54  31.15   0.00
==> mutect2_19.txt <==
165973.6274     1 day, 22:06:13 1625.34 5393.67 1598.53 1599.31 5304.61 102.87  0.00
==> mutect_21.txt <==
1419.4974       0:23:39 1125.20 4580.24 1101.30 1102.55 362.21  67.10   0.00
==> mutect2_1.txt <==
215570.6517     2 days, 11:52:50        1607.38 5404.89 1579.32 1581.15 9928.94 136.78  0.00
==> mutect2_20.txt <==
87936.4660      1 day, 0:25:36  1333.81 5393.47 1303.21 1304.49 2378.94 55.84   0.00
==> mutect2_21.txt <==
31767.5137      8:49:27 1241.53 5501.50 1210.05 1211.05 1029.50 21.78   0.00
==> mutect2_22.txt <==
65424.0151      18:10:24        1315.78 5393.84 1284.41 1285.63 1913.00 42.99   0.00
==> mutect_22.txt <==
2232.6226       0:37:12 1246.06 4580.24 1222.29 1223.62 712.41  78.19   0.00
==> mutect2_2.txt <==
189937.6815     2 days, 4:45:37 1535.52 5396.07 1503.79 1505.15 8586.79 119.77  0.00
==> mutect2_3.txt <==
141593.6697     1 day, 15:19:53 1548.27 5391.41 1519.81 1520.57 6159.18 91.39   0.00
==> mutect2_4.txt <==
113204.2565     1 day, 7:26:44  1432.26 5408.98 1400.68 1402.46 2423.45 72.86   0.00
==> mutect2_5.txt <==
117168.8867     1 day, 8:32:48  1482.88 5394.94 1451.24 1453.36 4578.30 75.65   0.00
==> mutect2_6.txt <==
142789.9733     1 day, 15:39:49 1547.14 5397.13 1518.93 1519.64 5609.93 91.24   0.00
==> mutect2_7.txt <==
148948.1393     1 day, 17:22:28 1545.62 5515.08 1517.29 1519.29 4926.46 93.47   0.00
==> mutect2_8.txt <==
103571.2659     1 day, 4:46:11  1555.79 5426.49 1524.32 1525.67 2596.15 66.94   0.00
==> mutect2_9.txt <==
102204.6028     1 day, 4:23:24  1556.36 5408.69 1526.38 1527.73 3265.65 65.40   0.00
==> mutect_2.txt <==
9308.3525       2:35:08 2035.54 4580.24 2011.67 2014.94 8306.65 442.30  0.00
==> mutect2_X.txt <==
53637.3633      14:53:57        1477.18 5378.54 1445.34 1446.48 2492.98 36.46   0.00
==> mutect_3.txt <==
6777.5392       1:52:57 1731.80 4580.24 1706.88 1709.02 5779.87 338.80  0.00
==> mutect_4.txt <==
5300.7566       1:28:20 1649.19 4580.24 1638.20 1638.52 4672.53 318.21  0.00
==> mutect_5.txt <==
5567.3555       1:32:47 1649.34 4580.24 1624.54 1626.43 4321.95 310.42  0.00
==> mutect_6.txt <==
6180.6757       1:43:00 1723.32 4580.24 1699.39 1701.28 4786.73 305.54  0.00
==> mutect_7.txt <==
6604.0332       1:50:04 1682.11 4580.24 1657.68 1659.80 4765.41 297.65  0.00
==> mutect_8.txt <==
4554.1054       1:15:54 1582.31 4580.24 1557.82 1564.30 4068.04 262.54  0.00
==> mutect_9.txt <==
4280.9887       1:11:20 1516.35 4580.24 1491.96 1496.41 4026.20 211.96  0.00
==> mutect_X.txt <==
3356.4529       0:55:56 1306.22 4580.24 1282.06 1283.43 814.54  199.17  0.00
==> normal_base_recalibrator_print_reads.txt <==
7333.5113       2:02:13 19376.15        25963.44        19355.18        19364.42        1.76    31430.47        0.00
==> normal_base_recalibrator.txt <==
3939.9578       1:05:39 16444.89        25965.17        16422.63        16431.80        27037.62        2.97    0.00
==> normal_L001_bwa_mem.txt <==
2234.3952       0:37:14 6870.79 7291.71 6866.65 6867.23 10296.33        39711.67        0.00
==> normal_L001_convert_alignment_to_sorted_bam.txt <==
3674.1591       1:01:14 7876.03 26597.21        7857.97 7862.03 54319.19        24833.54        0.00
==> normal_L002_bwa_mem.txt <==
2357.2039       0:39:17 6877.92 7291.71 6873.72 6874.49 10557.05        40379.54        0.00
==> normal_L002_convert_alignment_to_sorted_bam.txt <==
5430.6143       1:30:30 7767.41 26596.21        7747.61 7753.03 56225.77        25460.14        0.00
==> normal_mark_dups.txt <==
4972.0290       1:22:52 21101.26        26596.22        21081.06        21089.34        8985.15 23725.14        0.00
==> rna_mark_dups.txt <==
2748.3613       0:45:48 15598.45        26596.21        15578.65        15584.00        1.18    9703.38 0.00
==> strelka.txt <==
2223.0812       0:37:03 1799.47 2865.69 1569.11 1576.18 91426.98        20.17   0.00
==> tumor_base_recalibrator_print_reads.txt <==
14999.3291      4:09:59 21091.40        25963.44        21084.58        21086.95        8134.49 64833.70        0.00
==> tumor_base_recalibrator.txt <==
6228.1026       1:43:48 19438.90        25963.12        19416.99        19426.12        36039.72        4.61    0.00
==> tumor_indel_realigner.txt <==
1735.2163       0:28:55 2050.04 5219.57 2048.14 2049.17 35440.06        35960.85        0.00
==> tumor_L001_bwa_mem.txt <==
5687.1797       1:34:47 7638.33 8057.71 7633.55 7635.22 24849.09        88688.13        0.00
==> tumor_L001_convert_alignment_to_sorted_bam.txt <==
7133.6827       1:58:53 7803.98 26596.21        7785.31 7790.73 124347.63       55247.35        0.00
==> tumor_L002_bwa_mem.txt <==
5866.9096       1:37:46 7662.25 8057.71 7657.48 7659.15 26003.46        90356.66        0.00
==> tumor_L002_convert_alignment_to_sorted_bam.txt <==
7022.1991       1:57:02 7792.38 26596.21        7773.64 7779.07 126950.95       56813.34        0.00
==> tumor_mark_dups.txt <==
10748.2751      2:59:08 19735.49        26596.22        19718.01        19724.98        50041.64        51629.68        0.00