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P49711 CTCF (PTHR24404) and Q8NI51 CTCFL (PTHR24406) should probably be in the same tree #22

Open pgaudet opened 4 years ago

pgaudet commented 4 years ago

Similarity is very high

CLUSTAL O(1.2.4) multiple sequence alignment

SP|P49711|CTCF_HUMAN MEGDAVEAIVEESETFIKGKERKTYQRRREGG-QEEDACHL---------PQNQTDGGEV 50 SP|Q8NI51|CTCFL_HUMAN MAATE---ISVLSEQFTKIKELELMPEKGLKEEEKDGVCREKDHRSPSELEAERTSGAFQ 57

  • . * : .: :::..: ::.*.

SP|P49711|CTCF_HUMAN VQDVNSSVQMVMMEQLDPTLLQMKTEVMEGTVAPEAEAAVDDTQIITLQVVNMEEQPINI 110 SP|Q8NI51|CTCFL_HUMAN DSVLEEEVELV--------------------LAPS---EESEKYILTLQTVHFTSEAVEL 94 . ::..:: :. .:. :.*:: .: :::

SP|P49711|CTCF_HUMAN GELQLVQV------------PVPVTVPVATTSVEELQGAYENEVSKEGLAESEPMICHTL 158 SP|Q8NI51|CTCFL_HUMAN QDMSLLSIQQQEGVQVVVQQPGPGLLWLEEGPRQSLQQCVAISI------------QQEL 142 ::.:.: * : : :.* . .: :

SP|P49711|CTCF_HUMAN PLPEGFQVVKVGANGEVETLEQGELPPQEDPSWQ----------KDPDYQPPAKKTKKTK 208 SP|Q8NI51|CTCFL_HUMAN YSPQEMEVLQFHA------LEENVMVASEDSKLAVSLAETTGLIKLEEEQEKNQLLAERT 196 : ::::. :. : . . : * : : .

SP|P49711|CTCF_HUMAN KSKLRYTE------EGKDVDVSV--YDFEEEQQEGLLSEVNAEKVVGNMKPPKPTKIKKK 260 SP|Q8NI51|CTCFL_HUMAN KEQLFFVETMSGDERSDEIVLTVSNSNVEEQEDQPTAGQADAE-----KAKSTKNQRKTK 251 .: :. ...:: :: :.:::: .:.: . .: .

SP|P49711|CTCF_HUMAN GVKKTFQCELCSYTCPRRSNLDRHMKSHTDERPHKCHLCGRAFRTVTLLRNHLNTHTGTR 320 SP|Q8NI51|CTCFL_HUMAN GAKGTFHCDVCMFTSSRMSSFNRHMKTHTSEKPHLCHLCLKTFRTVTLLRNHVNTHTGTR 311 . ::: :. *.::**:.*: ::**:***

SP|P49711|CTCF_HUMAN PHKCPDCDMAFVTSGELVRHRRYKHTHEKPFKCSMCDYASVEVSKLKRHIRSHTGERPFQ 380 SP|Q8NI51|CTCFL_HUMAN PYKCNDCNMAFVTSGELVRHRRYKHTHEKPFKCSMCKYASVEASKLKRHVRSHTGERPFQ 371 *: :****.*.**:**

SP|P49711|CTCF_HUMAN CSLCSYASRDTYKLKRHMRTHSGEKPYECYICHARFTQSGTMKMHILQKHTENVAKFHCP 440 SP|Q8NI51|CTCFL_HUMAN CCQCSYASRDTYKLKRHMRTHSGEKPYECHICHTRFTQSGTMKIHILQKHGENVPKYQCP 431 *. **:*:***:** ::

SP|P49711|CTCF_HUMAN HCDTVIARKSDLGVHLRKQHSYIEQGKKCRYCDAVFHERYALIQHQKSHKNEKRFKCDQC 500 SP|Q8NI51|CTCFL_HUMAN HCATIIARKSDLRVHMRNLHAYSAAELKCRYCSAVFHERYALIQHQKTHKNEKRFKCKHC 491 *:***** :: :* ***.**:*****.:*

SP|P49711|CTCF_HUMAN DYACRQERHMIMHKRTHTGEKPYACSHCDKTFRQKQLLDMHFKRYHDPNFVPAAFVCSKC 560 SP|Q8NI51|CTCFL_HUMAN SYACKQERHMTAHIRTHTGEKPFTCLSCNKCFRQKQLLNAHFRKYHDANFIPTVYKCSKC 551 .*:*** * ****:: :* ***: ::* *::.: ****

SP|P49711|CTCF_HUMAN GKTFTRRNTMARHADNCAGPDGVEGENGGETKKSKRGRKRKMRSKKEDSSDSENAEPDLD 620 SP|Q8NI51|CTCFL_HUMAN GKGFSRWINLHRHSEKCGSGEAKSAASGKGR----RTRKRKQTILKEATKGQKEAAKGWK 607 : .: :::.. :. .. . * ** :...::* . .

SP|P49711|CTCF_HUMAN DNEDEEEPAVE----IEPEPEPQPVTPAPPPAKKRRGRPPGRTNQPKQNQPTAIIQVEDQ 676 SP|Q8NI51|CTCFL_HUMAN EAANGDEAAAEEASTTKGEQFPGEMFPVA--CRET----------------TARV-KEE- 647 : : : . : : . .:: * : :

SP|P49711|CTCF_HUMAN NTGAIENIIVEVKKEPDAEPAEGEEEEAQPAATDAPNGDLTPEMILSMMDR 727 SP|Q8NI51|CTCFL_HUMAN -----------------------------------VDEGVTCEMLLNTMDK 663 : .:* *:. **:

Thanks, Pascale