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parklab / HiNT

HiC for copy Number variation and Translocation detection
MIT License
36 stars 8 forks source link

Is background matrices necessary? #13

Open JiaoLaboratory opened 3 years ago

JiaoLaboratory commented 3 years ago

hello, I want to run hint tl for other species , Is background matrices necessary ?

XiaoTaoWang commented 2 years ago

Hi, this is Xiaotao. We recently developed a new method called EagleC (https://github.com/XiaoTaoWang/EagleC) for detecting SVs from 3C-based data. EagleC does not need a background matrix for SV detection and so support any genome in theory. Take a look and hope it is useful in your project!