Two more sequences seem to be from the same outbreak, from different sequencers. In this case, one sequence is labeled as index patient and also Kuchica, matching Patient 1 from above.
The other sequence is labeled Skopje and "infected healthcare worker", matching the description from the papers above. So geolocation and dates could be narrowed for these as well.
Describe the possible issue
Geolocation is not as precise as it can be, based on further information from the isolate name.
Evidence of the problem
https://pathoplexus.org/seq/PP_000RFLV.2: Admin 1 is
Kriva Palanka
, see also -> https://www.ncbi.nlm.nih.gov/nuccore/PQ031236.1, https://www.geonames.org/863869/kriva-palanka.htmlhttps://pathoplexus.org/seq/PP_000RFMT.2 has Admin 1:
Arachinovo
, https://www.geonames.org/863831/opstina-aracinovo.htmlhttps://pathoplexus.org/seq/PP_000RF4U.2 has Admin 1:
Karbinci
, City:Kucica
, see https://www.geonames.org/788935/kucica.html (also spelled Kuchica) [Patient 1]All first parts of the isolate names map perfectly to North Macedonian locations.
The oldest sample (Kuchica) is described in two associated publications:
https://assets-eu.researchsquare.com/files/rs-4360716/v1/21a390d9-967e-402f-bd9f-c9e6ad3eaf8a.pdf?c=1715100422
https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2023.28.34.2300409
Suggested change
Aside
Two more sequences seem to be from the same outbreak, from different sequencers. In this case, one sequence is labeled as index patient and also Kuchica, matching Patient 1 from above.
The other sequence is labeled Skopje and "infected healthcare worker", matching the description from the papers above. So geolocation and dates could be narrowed for these as well.
https://pathoplexus.org/seq/PP_000RFJZ.2 https://pathoplexus.org/seq/PP_000RFKX.2