pcingola / Epistasis

6 stars 10 forks source link

Additional information from Expression, Tissue, Celular localization, etc. #12

Open pcingola opened 9 years ago

pcingola commented 9 years ago

How do we incorporate all these elements into our "prior":

i) Expression from GTex (tissue specific, gene, transcript and exon abudances)

ii) Pathway from REACTOME, KEGG, BIOCARTA, etc.

iii) Celular localization of the proteins (NextProt).

iv) Protein-Protein interaction data (PPI)

Can we add a logistic model to increase these priors?

pcingola commented 9 years ago

Also add specific GeneSets (e.g. Tanya's Diabetes)