Closed fgrunewald closed 5 months ago
1) C1C(F)C(n2c3ncn(=O)c(N)c3nc2)OC1CO
n8 is uncharged and has 4 bonds even without being aromatic. So it gets pruned, and should break.
2) Cc1nc(Cl)c(C)n(=O)c1Cl
Same for n7.
3) Cc1n(=O)c(Cl)c(C)nc1
n2
4) c1c(c3nc(Cl)cn(=O)c3c2ccc(Cl)cc2)ccc(Cl)c1
n7
5) O=C1CCC(N1)c2cccn(=O)c2
n10
Smiles that are aromatic and worked before the latest aromatic update: