perslab / depict

DEPICT code, instructions and an example
GNU General Public License v3.0
48 stars 22 forks source link

DEPICT not working with results from HRC imputed data #15

Open oyhel opened 5 years ago

oyhel commented 5 years ago

I have results from an HRC v1.1 imputed dataset. When using the results (passing the pruned top hits) to DEPICT I get information that the marker is not found in the genotyped data. I assume this is due to the HRC markers not being in the 1000G reference. Question is if HRC imputed data will be supported, and if not, how would I go about updating the reference data?

I did try to look into the background data but the 1000G markers seems tightly integrated with the rest of the reference data so I am not sure how to do this.

Any help would be greatly appreciated!