Vignettes: Creating an Obesity ADVS

[manciniedoardo]

Base the vignette on the BDS Findings vignette from {admiral} (also uses ADVS – lucky us!) but don't duplicate sections that would be identical. See {admiralpeds} ADVS vignette as an example.​

Suggestion on contest/structure:

• Explain what the common obesity endpoints are.​
• Explain how to add them to ADVS using {admiral} tools.​ Could consider criterion flags - we have a brand-new function in {admiral}, derive_vars_crit_flag(). ​

[Siddhesh2097]

Hi @kathrinflunkert , after discussing with the team in the last meeting, I think we can include the following in our vignette.

1. Adding derive_param_bmi. The reason is that "BMI collected on CRF" / "system calculated BMI" is not considered and we re-calculate BMI in ADVS, so it will be good to have this in vignette as well.

2. Additional parameters that we have added , WSTCIR, HIPCIR and BMI.

3. Categorical variables

   • CHGCAT for Change in SYSBP, DIABP, PULSE
   • BASECAT for BMI baseline categories ( Underweight, Overweight, Obese class I, Obese class II ...)
   • AVALCAT for BMI categories , same as above.

4. The new derive_vars_crit_flag for >= 5%, >= 10%, >= 15% and so on weight reduction

Let me know what you think of the above and if there is anything we missed