Cannot find `tcr_complex_model.static.linuxgccrelease `

Hi,

Nice to hear that you're interested in our TCR-pMHC modeling algorithm. That code and program were under development early last year, but the code was not finalized and merged into the main Rosetta code base, so the executable is not currently publicly available. However, we've recently implemented an improved version of TCRmodel that uses an optimized version of AlphaFold to model TCR-pMHC complexes, and that outperforms our Rosetta-based algorithm. It's not available as a standalone version, so it's currently only accessible via the TCRmodel server interface. Sometime soon (in the next few months), it should be available on Github too.

Best, Brian

Brian G. Pierce, Ph.D. Assistant Professor Department of Cell Biology and Molecular Genetics Institute for Bioscience and Biotechnology Research University of Maryland 9600 Gudelsky Drive Rockville, MD 20850 Office: 240-314-6271 <(240)%20314-6271> piercelab.ibbr.umd.edu

On Thu, Jan 12, 2023 at 4:35 AM Quw @.***> wrote:

Hi,

I want to model TCR-pMHC complex on my own server and I have downloaded rosetta.binary.ubuntu.release-334 and installed the rosetta. However, there is no such tcr_complex_model.static.linuxgccrelease in the rosetta.binary.ubuntu.release-334/main/source/bin/. I only can find tcrmodel.static.linuxgccrelease for TCR complex (CDRalpha-CDRbeta) structure generation.

Could you help me solve this problem?

— Reply to this email directly, view it on GitHub https://github.com/piercelab/tcrmodel/issues/1, or unsubscribe https://github.com/notifications/unsubscribe-auth/ABSP6VNZWS742S3WP6WTM63WR7F5PANCNFSM6AAAAAATZAZZPU . You are receiving this because you are subscribed to this thread.Message ID: @.***>

piercelab / tcrmodel

Cannot find `tcr_complex_model.static.linuxgccrelease ` #1

Best, Brian