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pinder-org / pinder

PINDER: The Protein INteraction Dataset and Evaluation Resource
https://pinder-org.github.io/pinder/
Apache License 2.0
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Predicting Interactions #7

Closed cerabinowitz closed 2 weeks ago

cerabinowitz commented 1 month ago

Hi, I’m interested in whether PINDER can predict interactions between two sequences or structures. Is there a method or feature within PINDER for this? Any guidance or insights would be appreciated. Thanks!

danielkovtun commented 1 month ago

Hi -- no, PINDER does not provide any models for co-folding or docking inference. It provides a dataset and framework for training and evaluating new methods with a particular attention to data splits to minimize information leakage and maximize generalizability.

We have provided initial templates as inspiration for how we ran the physics-based methods evaluated in the benchmark included in our publication. Feel free to check out the pinder.methods package if that is of interest.