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In response to [this](https://github.com/pingcap/tidb/issues/34956#issuecomment-1189836942):
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Bug Report
BR version [release-version=v5.4.0] [git-hash=55f3b24c1c9f506bd652ef1d162283541e428872] [git-branch=heads/refs/tags/v5.4.0] [go-version=go1.16.4] [utc-build-time="2022-01-25 08:36:34"]
Panic stack github.com/tikv/client-go/v2/internal/client.interceptedClient.SendRequest(0x40439a8, 0xc000c5b500, 0x4065210, 0xc0008fc580, 0xc000f99180, 0x39, 0xc00f6f1e00, 0x6fc23ac00, 0x203003, 0x203003, ...)
/nfs/cache/mod/github.com/tikv/client-go/v2@v2.0.0-rc.0.20211229051614-62d6b4a2e8f7/internal/client/client.go:410 +0x275 /nfs/cache/mod/github.com/tikv/client-go/v2@v2.0.0-rc.0.20211229051614-62d6b4a2e8f7/internal/client/client_collapse.go:74 +0x12a /nfs/cache/mod/google.golang.org/grpc@v1.29.1/clientconn.go:514 github.com/tikv/client-go/v2/internal/client.(RPCClient).SendRequest(0xc000c5b500, 0x4065210, 0xc0008fc580, 0xc000f99180, 0x39, 0xc00f6f1e00, 0x6fc23ac00, 0x0, 0x0, 0x0) github.com/tikv/client-go/v2/internal/client.interceptedClient.SendRequest(0x40439a8, 0xc000c5b500, 0x4065210, 0xc0008fc580, 0xc000f99180, 0x39, 0xc00f6f1e00, 0x6fc23ac00, 0x203003, 0x203003, ...) I0524 03:58:28.807851 9 backup.go:100] panic: runtime error: invalid memory address or nil pointer dereference goroutine 13166 [running]: github.com/tikv/client-go/v2/internal/client.reqCollapse.SendRequest(0x4045a00, 0xc000adc030, 0x4065210, 0xc0008fc580, 0xc000f99180, 0x39, 0xc00f6f1e00, 0x6fc23ac00, 0x39e0f40, 0x1, ...) /nfs/cache/mod/github.com/tikv/client-go/v2@v2.0.0-rc.0.20211229051614-62d6b4a2e8f7/tikv/kv.go:538 +0x145 I0524 03:58:28.807762 9 backup.go:93] [signal SIGSEGV: segmentation violation code=0x1 addr=0x228 pc=0x1d32b75] google.golang.org/grpc.(ClientConn).GetState(...) github.com/tikv/client-go/v2/tikv.(KVStore).updateSafeTS.func1(0x40439d0, 0xc000adc040, 0xc000a90640, 0x4065210, 0xc0008fc580, 0xc010991d20, 0x11, 0xc000f99180, 0x39) /nfs/cache/mod/github.com/tikv/client-go/v2@v2.0.0-rc.0.20211229051614-62d6b4a2e8f7/tikv/kv.go:540 +0x165 created by github.com/tikv/client-go/v2/tikv.(KVStore).updateSafeTS /nfs/cache/mod/github.com/tikv/client-go/v2@v2.0.0-rc.0.20211229051614-62d6b4a2e8f7/internal/client/client_interceptor.go:42 +0x1e9
It is about https://jira.tidbcloud.com/browse/TCOC-451