pneuvial / c3co

Inferring cancer cell clonality from copy-number data
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Task: Let the possibility to include an intercept term in the model to describe normal subclones #68

Open jchiquet opened 5 years ago

jchiquet commented 5 years ago

We discussed with @pneuvial and @HenrikBengtsson about the opportunity to have a working version of the model that includes the (true) intercept.

We start by adding an option intercept=TRUE|FALSE in positiveFusedLasso() (and later, in the above functions as well).

Basic maths derivation attached, do not have time to write them clean

img_20190222_085123270 img_20190222_085128019

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