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polyactis / Accucopy

Accucopy is a computational method that infers Allele-Specific Copy Number alterations from low-coverage low-purity tumor sequencing data.
https://www.yfish.org/software/Accucopy
GNU General Public License v3.0
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Using hole exome sequencing data #2

Open probalica19 opened 3 years ago

probalica19 commented 3 years ago

Hi,

Great tool and documentation! I've read on your documentation page that the tool might work with whole exome data - could you please provide more information on that? Is possible and is it recommended?

Thank you a lot in advance!

probalica

polyactis commented 3 years ago

We have some users test it. As long as your exome contains enough copy number alterations, it should work. The procedure is identical to the WGS data. Two bam files, etc...

On Fri, Oct 9, 2020, 6:53 PM probalica19 notifications@github.com wrote:

Hi,

Great tool and documentation! I've read on your documentation page that the tool might work with whole exome data - could you please provide more information on that? Is possible and is it recommended?

Thank you a lot in advance!

probalica

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wangshun1121 commented 3 years ago

或许可以考虑，在输入的时候，给定一个bed格式的目标区间，然后分析的时候仅仅考虑这一部分？