signalling

[ValWood]

consider for:

• [ ] SPCC63.08c atg1 autophagy serine/threonine protein kinase Atg1
• [ ] SPAC1556.03 azr1 serine/threonine protein phosphatase Azr1
• [ ] SPBC18H10.15 cdk11 serine/threonine protein kinase Cdk11
• [x] SPAC644.06c cdr1 NIM1 family serine/threonine protein kinase Cdr1/Nim1
• [x] SPCC1450.11c cek1 serine/threonine protein kinase Cek1
• [x] SPAC23C11.11 cka1 serine/threonine protein kinase Cka1
• [ ] SPBC1347.06c cki1 serine/threonine protein kinase involved in endocytosis Cki1
• [ ] SPBP35G2.05c cki2 serine/threonine protein kinase Cki2
• [x] SPBC1D7.03 clg1 cyclin-like protein involved in autophagy Clg1 (predicted)
• [x] SPAC23A1.06c cmk2 MAPK-activated protein kinase Cmk2
• [x] SPAC6B12.15 cpc2 RACK1 ortholog Cpc2
• [ ] SPAC1093.03 fig4 inositol polyphosphate phosphatase Fig4 (predicted)
• [x] SPBC211.03c gea1 guanyl-nucleotide exchange factor (predicted)
• [x] SPAC1687.15 gsk3 serine/threonine protein kinase Gsk3
• [x] SPBC8D2.01 gsk31 serine/threonine protein kinase Gsk31 (predicted)
• [ ] SPBC3H7.15 hhp1 serine/threonine protein kinase Hhp1
• [ ] SPAC23C4.12 hhp2 serine/threonine protein kinase Hhp2
• [ ] SPCC970.08 kcs1 inositol polyphosphate kinase Kcs1 (predicted)
• [ ] SPAC1D4.11c lkh1 dual specificity protein kinase Lkh1
• [ ] SPAC343.19 lsb6 1-phosphatidylinositol 4-kinase Lsb6 (predicted)
• [ ] SPBC530.13 lsc1 Lsk1 associated cyclin
• [ ] SPAC2F3.15 lsk1 P-TEFb-associated cyclin-dependent protein kinase Lsk1
• [ ] SPAC11E3.06 map1 MAD - [ ] S-box transcription factor Map1
• [ ] SPBC8D2.19 mde3 serine/threonine protein kinase, meiotic Mde3
• [ ] SPCC1840.01c mog1 Ran GTPase binding protein Mog1
• [ ] SPCC1020.10 oca2 serine/threonine protein kinase Oca2
• [ ] SPAC3C7.06c pit1 serine/threonine protein kinase, meiotic Pit1
• [x] SPAC16C9.07 pom2 DYRK family protein kinase Pom2
• [x] SPAC823.15 ppa1 minor serine/threonine protein phosphatase Ppa1
• [x] SPBC16H5.07c ppa2 serine/threonine protein phosphatase Ppa2
• [x] SPBC26H8.05c ppe2 serine/threonine protein phosphatase, PP4 complex subunit Ppe2
• [ ] SPAC110.01 ppk1 serine/threonine protein kinase Ppk1 (predicted)
• [ ] SPAC3H1.13 ppk13 serine/threonine protein kinase Ppk13, involvedin negative regulation of vacuole fusion (predicted)
• [ ] SPAC4G8.05 ppk14 serine/threonine protein kinase Ppk14 (predicted)
• [ ] SPAC823.03 ppk15 serine/threonine protein kinase Ppk15 (predicted)
• [ ] SPAC890.03 ppk16 serine/threonine protein kinase Ppk16 (predicted)
• [ ] SPBC119.07 ppk19 serine/threonine protein kinase Ppk19
• [ ] SPBC1861.09 ppk22 serine/threonine protein kinase Ppk22 (predicted)
• [ ] SPBC21.07c ppk24 serine/threonine protein kinase Ppk24
• [ ] SPBC725.06c ppk31 serine/threonine protein kinase Ppk31
• [ ] SPCC162.10 ppk33 serine/threonine protein kinase Ppk33 (predicted)
• [ ] SPCP1E11.02 ppk38 Ark1/Prk1 family protein kinase Ppk38
• [ ] SPAC1805.01c ppk6 serine/threonine protein kinase Ppk6 (predicted)
• [ ] SPAC22G7.08 ppk8 serine/threonine protein kinase Ppk8 (predicted)
• [ ] SPAC23H4.02 ppk9 serine/threonine protein kinase Ppk9 (predicted)
• [ ] SPAC4A8.03c ptc4 protein phosphatase 2C Ptc4
• [x] SPAC227.15 reg1 protein phosphatase regulatory subunit Reg1 (predicted)
• [x] SPBC32F12.09 rum1 CDK inhibitor Rum1
• [x] SPAC4A8.12c sds22 protein phosphatase regulatory subunit Sds22
• [x] SPBC646.13 sds23 PP2A-type phosphatase inhibitor Sds23/Moc1
• [x] SPAC19A8.01c sec73 guanyl-nucleotide exchange factor Sec73 (predicted)
• [x] SPAC26F1.01 sec74 guanyl-nucleotide exchange factor Sec74 (predicted)
• [x] SPBC1289.03c spi1 Ran GTPase - [ ] Spi1
• [x] SPBC21C3.18 spo4 serine/threonine protein kinase Spo4
• [x] SPCC1322.08 srk1 MAPK-activated protein kinase Srk1
• [ ] SPAC1071.12c stp1 protein tyrosine phosphatase Stp1, unknown biological role
• [x] SPBC1734.14c suc1 cyclin-dependent protein kinase regulatory subunit Suc1
• [ ] SPAC22F3.13 tsc1 hamartin
• [x] SPAC4F10.04 ypa1 protein phosphatase type 2A regulator, PTPA family Ypa1
• [x] SPAC1782.05 ypa2 protein phosphatase type 2A regulator, PTPA family Ypa2
• [x] SPAC9E9.07c ypt2 GTPase Ypt2
• [x] SPAC1B3.11c ypt4 GTPase Ypt4
• [x] SPBC405.04c ypt7 GTPase Ypt7
• [x] SPAC6B12.13 protein phosphatase type I regulatory subunit (predicted)
• [x] SPBC17A3.03c phosphoprotein phosphatase (predicted)
• [x] SPBC17A3.06 phosphoprotein phosphatase (predicted)
• [ ] SPCC297.05 DENN domain Rab GDP-GTP exchange factor, implicated in endosomal transport (predicted)

[ValWood]

@Antonialock which of these do you think should be annotated to signalling?

[ValWood]

I guess it depends in the terminal kinase in a signalling pathway is involved in signal trasduction/signaling?

[ValWood]

I think these are all signalling. I used to annotate them all to signalling but I stopped a few years ago. However, I have never come across a serine/threonine protein kinase, or a protein phosphatase that isn't involved in signalling. I think it's safe. I made a GAF...

[ValWood]

If any look wrong, delete them from here: external-go-data/GO-0023052_gap_filling.gaf.txt