search

pombase / curation

PomBase curation
7 stars 0 forks source link

ssp1 starvation stress response #1935

Closed ValWood closed 5 years ago

ValWood commented 6 years ago

Mutations in the fission yeast CaMKK-like protein kinase Ssp1 generate defects in cell-cycle progression, nutrient sensing, and cell polarity [9–11].

(no nutrient sensing defect captured)

ValWood commented 6 years ago

I don't know which ppaper this was from but these are the ones supporting a similar statement in another paper

  1. Matsusaka T, Hirata D, Yanagida M, Toda T. 1995. A novel protein kinase gene ssp1 is required for alteration of growth polarity and actin localization in fission yeast. EMBO J 14:3325–3338.

  2. Rupes I, Jia Z, Young PG. 1999. Ssp1 promotes actin depolymerization and is involved in stress response and new end take-off control in fission yeast. Mol Biol Cell 10:1495–1510. https://doi.org/10.1091/mbc.10.5 .1495.

  3. Valbuena N, Moreno S. 2012. AMPK phosphorylation by Ssp1 is required for proper sexual differentiation in fission yeast. J Cell Sci 125: 2655–2664. https://doi.org/10.1242/jcs.098533.

  4. Hanyu Y, Imai KK, Kawasaki Y, Nakamura T, Nakaseko Y, Nagao K, Kokubu A, Ebe M, Fujisawa A, Hayashi T, Obuse C, Yanagida M. 2009. Schizosaccharomyces pombe cell division cycle under limited glucose requires Ssp1 kinase, the putative CaMKK, and Sds23, a PP2A-related phosphatase inhibitor. Genes Cells 14:539 –554. https://doi.org/10.1111/j.1365 -2443.2009.01290.x.

  5. Freitag SI, Wong J, Young PG. 2014. Genetic and physical interaction of Ssp1 CaMKK and Rad24 14-3-3 during low pH and osmotic stress in fission yeast. Open Biol 4:130127. https://doi.org/10.1098/rsob.130127.

ValWood commented 5 years ago

actually this does have meiotic nuclear division and negative regulation of TORC1 signaling