pombase / curation

PomBase curation
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GTPases regulating cytokinesis #3164

Open ValWood opened 2 years ago

ValWood commented 2 years ago

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC452188/ "Rho1 GTPase activates β-1,3-glucan synthases as a regulatory subunit [23–26]. The α-glucan synthase Ags1 is regu- lated by Rho1 and Rho2 GTPases via the protein kinase C [27,28]."

gef1 -> cdc42 -> bgs1 -> primary septum formation scd1 -> cdc42 -| bgs4 -> secondary septum formation rga4/6 -| cdc42 -> abscission

THIS IS A GOOD EXAMPLE FOR GO QUESTIONS ABOUT REGULATION

ValWood commented 2 years ago

PMID:31719163 has a good model supported by genetics, but not curated:

39719163 gef1-cdc42-scd2-scd1

GO before:

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