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PomBase curation
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Transcriptional gene silencing (TGS) facultative heterochromatin assembly plus surveillance) #3641

Open ValWood opened 5 months ago

ValWood commented 5 months ago

https://www.pombase.org/reference/PMID:25428589 (nc-tgp1 transcriptional gene silencing by lncRNA) uses heterochromatin assembly, and surveillance together to silence genes "pretranscrptionally" https://www.pombase.org/reference/PMID:24493644 (lnc-pho1 transcriptional gene silencing by lncRNA) I'm still not sure we should directly annotate the lncRNAs with a function? need a child of GO:0031047 regulatory ncRNA-mediated gene silencing for ncRNA Underscoring a direct role, cells defective in lncRNA production show de-repression of target genes https://www.pombase.org/reference/PMID:28765164 (lnc-nam1 transcriptional gene silencing by lncRNA) https://www.pombase.org/reference/PMID:27165520 (lncRNA prt transcriptional gene silencing by lncRNA )

https://www.pombase.org/reference/PMID:24210919 these should probably be surveillance not heterochromatin assembly (although directly causally upstream)

ValWood commented 4 months ago

also pho84 (targets of surveillance TGS)