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PomBase curation
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Early cytokinetic node formation #3679

Closed ValWood closed 1 month ago

ValWood commented 6 months ago

I think we have most of the cytokinetic network, but are missing some of these early steps:

Plo1-induced export from the nucleus of the anillin-like protein Mid1, reinforces division plane positioning in the cell middle (Almonacid et al., 2009),

Plo1 also activates Mid1, which becomes competent for the sequential recruitment of essential ring components (Almonacid et al., 2011): Mid1 first engages the IQGAP protein Rng2 and myosin II light chain Cdc4, heavy chain Myo2 and regulatory light chain Rlc1.

We are also missing myo2 and rlc2 (if these are directly recruited by mid1….)

PCarme commented 5 months ago

Note to self - see references : Motegi, F., M. Mishra, M. K. Balasubramanian, and I. Mabuchi. 2004. Myosin II reorganization during mitosis is controlled temporally by its dephosphoryla- tion and spatially by Mid1 in fission yeast. J. Cell Biol. 165:685–695 Wu, J. Q., J. R. Kuhn, D. R. Kovar, and T. D. Pollard. 2003. Spatial and temporal pathway for assembly and constriction of the contractile ring in fission yeast cytokinesis. Dev. Cell 5:723–734

Papers already curated.

PCarme commented 5 months ago

Uncurated publication : PMID:22427686 It was actually sent to the author in 2014, with 6 reminders (last sent in 2020). Should I curate this myself ?

ValWood commented 5 months ago

Should I curate this myself ? I sent a reminder, they usually curate

PCarme commented 1 month ago

Uncurated publication : PMID:22427686 It was actually sent to the author in 2014, with 6 reminders (last sent in 2020). Should I curate this myself ?

In the end I went on and curated this one. I think we should have the steps of recruitments of the different factors covered in GO MF at this point. Still need to annotate the activation of mid1 by plo1.

PCarme commented 1 month ago

Uncurated publication : PMID:22427686 It was actually sent to the author in 2014, with 6 reminders (last sent in 2020). Should I curate this myself ?

In the end I went on and curated this one. I think we should have the steps of recruitments of the different factors covered in GO MF at this point.

ValWood commented 1 month ago

OK, we can probably close this?