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pombase / curation

PomBase curation
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PMID:25356590 #3708

Open ValWood opened 1 month ago

ValWood commented 1 month ago

Multifaceted genome control by Set1 Dependent and Independent of H3K4 methylation and the Set1C/COMPASS complex.

Deletion of specific components of COMPASS affects the integrity of the complex and sta- bility of Set1 [31,48,102–105]. The deletion of Spp1, Swd1, Swd2, and Swd3 significantly lowers the protein levels of Set1 [48].

ValWood commented 1 month ago

Set1 proteins were barely detectable in swd1Δ and swd3Δ and were noticeably reduced in swd2Δ and spp1Δ mutants, but were minimally affected by the loss of Ash2, Sdc1, and Shg1 [48].

ValWood commented 1 week ago

This is the one I sent a session for. No hurry for this, I'm just trying to assign some tickets

PCarme commented 5 days ago

I have curated this one, it is now awaiting approval. I would appreciate if you could double check this one, I am not entirely sure of all the FYPO terms I have used/suggested to annotate the phenotypes, and I feel like my GO annotations might be missing some elements...

ValWood commented 2 days ago

I think this looks fine. Could also add retrotransposon silencing by heterochromatin formation (or a descendant?)

but this term is a bit strange, I think there are still issues in the heterochromatin formation processes, but at least if we capture it the annotation will "move around" with any corrections.

PCarme commented 2 days ago

I think I have already annotated to this term, or to a similar one, no ?

ValWood commented 2 days ago

Yes sorry, I noted it because I wanted to report a GO missing parent, but the annotation was present, and correct!