pombase / curation

PomBase curation
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zinc binding sites #3756

Open ValWood opened 1 month ago

ValWood commented 1 month ago

could you provide the list of proteins that have zinc-binding sites based on UniProt?

kimrutherford commented 1 month ago

There are some binding sites with annotations like this:

BINDING 229; /ligand="Zn(2+)"; /ligand_id="ChEBI:CHEBI:29105"; /ligand_note="catalytic"; /evidence="ECO:0000250";

Are those the ones you're after?

(That annotation is for SPAC17A5.04c)

ValWood commented 1 month ago

Exactly!

kimrutherford commented 1 month ago

188 genes:

zinc_binding_from_uniprot_data.tsv.txt

ValWood commented 1 month ago

Task: 1: Check the source and ask UniProt if these are suitable for GO zinc binding (or why they don't get included in the rule base)