mcl1 no longer has DNA replication annotation

[pombase-admin]

should be possible to add by IC or ISS if not by EXP

Original comment by: ValWood

[pombase-admin]

• Description has changed:

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 should be possible to add by IC or ISS if not by EXP

• status: open --> closed
• assigned_to: Midori Harris

Original comment by: mah11

[pombase-admin]

for now, have added IC from pol alpha/primase complex

also claimed 3 papers in canto, which will complete curation of PubMed hits (as of today, anyway)

Original comment by: mah11

[pombase-admin]

Upon further reading, thinking, etc. I am now convinced that Mcl1 is not a bona fide subunit of the pol alpha:primase complex (the complex is well defined as having 4 subunits, and in pombe they're Pol1, Spb70, Spp1 and Spp2). I've therefore removed the GO:0005658 CC annotations and the IC from them, although I suppose I could put them back with the "colocalizes_with" qualifier if you prefer.

There's now IGI annotation (with dna2 or rad2) to Okazaki fragment processing, so mcl1 still has a path to DNA replication.

Original comment by: mah11

[pombase-admin]

sounds good if the process is there

Original comment by: ValWood

[pombase-admin]

fyi, there are a couple of mcl1 papers that I'll leave for you or Antonia to approve, because I think there are a couple of "should we infer a GO BP from that phenotype" grey areas ... just watch the needs-approval list, I guess

Original comment by: mah11

[pombase-admin]

was about to do this but these sessions are now through let me knwo if I need to look at anything

v

Original comment by: ValWood