drugs list

[pombase-admin]

Can be added as "ex_tools" if we know target List could go on wiki or static web page. Maybe Susan maintains a more complete resource oon her website? need to check

alpha-amanitin Pol II alverine citrate proteasome /lipid synthesis? amiloride sodium transporter inhibitor amphotericin sterol biosynthesis inhibitor/ create pores cause lysis anisomycin translation inhibitor antifunagl azoles sterol biosynthesis inhibitors Arborcandin C 1,3-beta-Glucan Sunthase benomyl destabilizes microtubules bleomycins fungal cell wall sptation and cytokinesis inhibitors brefeldin/monensin intracellular transport calcofluor White Interferes with cell wall synthesis camptothecin target topoisomerase 1 Top1 canavanine L-arginine antimetabolite naturally occuring (alfafa) chloramphenicol Protein synthesis inhibitor compactin ergosteol bio CT2108A and B fatty acid synthase cyclohexamide translation inhibitor cycloheximide Pol I cyclosporin A cyclophilin dihydromotuporamine C proteasome/lipid synthesis? echinocandin Interfere with cell wall synthesis fenpropimorph proteasome /lipid synthesis? hydroxyurea ribonucleotide reductase, replication fork stalling hygromycin B translation inhibitor
isopropyl N-3-chlorophenyl carbamatevspindle poison itraconazole
latrunculin inhibits actin polymerization leptomycin B nuclear export receptor Crm1 lovastatin competative inhibitor of HMGR methyl-2-benzimidazolecarbamate reversible MT inhibitor natamycin blocks fungal growth by binding specifically to ergosterol without permeabilizing the membrane nystatin ergosterol biosynthesis;(antifungal; ergosta-5,7,22,24,(28)-tetraenol binding oxazolidinones Protein synthesis inhibitor phleomycin DNA strand breaks pravastatin HMGR inhibitor ricin splcieosome independent splicing? translation sanglifehrin A cyclophilin tagetitoxin/tagetin Pol III taurosporine protein kinase inhibitor thialysine naturalyl occuring lysine analogue trichostatin A (TSA) histone deacetylase tunimycin inhibits N-glycosylation zaragozic acid inhibits N-glycosylation

Original comment by: ValWood

[pombase-admin]

• priority: 5 --> 1

Original comment by: ValWood

[pombase-admin]

moved to wiki

https://sourceforge.net/apps/trac/pombase/wiki/DrugTargets

Original comment by: mah11

[pombase-admin]

• status: open --> closed

Original comment by: mah11